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07-383

Anti-Akt3/PKBγ Antibody

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
15


biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... AKT3(10000)

General description

~60 kDa

Immunogen

peptide corresponding to amino acids 119-131 of human Akt3/PKBgamma

Application

Anti-Akt3/PKBγ Antibody is an antibody against Akt3/PKBγ for use in IP & WB.

Biochem/physiol Actions

Recognizes Akt3/PKBγ.

Physical form

Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.

Analysis Note

Control
IGF-I stimulated HEK293 cell lysates
routinely evaluated by immunoprecipitating active Akt3/PKBγ from IGF-I stimulated HEK293 cell lysates.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: AB3136

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
05-78005-631HPA026441
biological source

rabbit

biological source

mouse

biological source

mouse

biological source

rabbit

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody form

purified antibody

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

clone

polyclonal

clone

GMA104, monoclonal

clone

monoclonal

clone

polyclonal

species reactivity

human

species reactivity

human

species reactivity

mouse, human

species reactivity

human

UniProt accession no.

Q9Y243

UniProt accession no.

Q9Y243

UniProt accession no.

Q9Y6K9

UniProt accession no.

Q9Y243


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Storage Class

10 - Combustible liquids

wgk

WGK 1



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Conrad P Hodgkinson et al.
Biochemistry, 41(32), 10351-10359 (2002-08-07)
Protein kinase B (PKB), also known as Akt, is a serine/threonine protein kinase controlled by insulin, various growth factors, and phosphatidylinositol 3-kinase. Full activation of the PKB enzyme requires phosphorylation of a threonine in the activation loop and a serine
Anna Joy et al.
Journal of neuro-oncology, 130(1), 43-52 (2016-10-21)
The growth factor receptor/PI3K/AKT pathway is an important drug target in many cancers including Glioblastoma. AKT, a key node in the pathway, has 3 isoforms, AKT1, AKT2 and AKT3. Here we investigate their role in GBM. We find each activated
François Fabi et al.
PloS one, 12(5), e0177387-e0177387 (2017-05-06)
Infertility is constantly increasing in Canada, where 16% of Canadian couples are experiencing difficulty conceiving. It is thought that infertility can emanate from the dysregulated communication between the embryo and the maternal endometrium. In order to allow for this window



Global Trade Item Number

SKUGTIN
07-38304053252323072

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