693243

(S)-Ru(OAc)₂(SEGPHOS^®)

• Synonym(s): Diacetato[(S)-(−)-5,5′-bis(diphenylphosphino)-4,4′-bi-1,3-benzodioxole]ruthenium(II)
• Empirical Formula (Hill Notation): C₄₂H₃₄O₈P₂Ru
• CAS Number: 373650-12-5
• Molecular Weight: 829.73
• UNSPSC Code: 12352005
• PubChem Substance ID: 329761576
• NACRES: NA.22
• MDL number: MFCD09753024

Properties

• form: powder
• Quality Segment: 100
• reaction suitability: reagent type: catalyst; core: ruthenium; reaction type: Noyori Asymmetric Hydrogenation
• functional group: phosphine
• storage temp.: 2-8°C
• SMILES string: [Ru+2].P(c8ccccc8)(c7ccccc7)c1c(c6c(cc1)OCO6)c2c3c(ccc2P(c5ccccc5)c4ccccc4)OCO3.[O-]C(=O)C.[O-]C(=O)C
• InChI: 1S/C38H28O4P2.2C2H4O2.Ru/c1-5-13-27(14-6-1)43(28-15-7-2-8-16-28)33-23-21-31-37(41-25-39-31)35(33)36-34(24-22-32-38(36)42-26-40-32)44(29-17-9-3-10-18-29)30-19-11-4-12-20-30;2*1-2(3)4;/h1-24H,25-26H2;2*1H3,(H,3,4);/q;;;+2/p-2
• InChI key: BHGLLIGZFQVMBJ-UHFFFAOYSA-L

Description

Application

Takasago Ligands and Complexes for Asymmetric Reactions

(S)-Ru(OAc)₂(SEGPHOS^®) can be used as a catalyst:

• To prepare highly chemo, enantio, and diastereoselective primary β-amino lactams by asymmetric reductive amination of racemic β-keto lactams.
• To synthesize chiral primary diarylmethylamines and sterically bulky benzylamines from diaryl and sterically hindered ketones via asymmetric reductive amination reaction.
• For the conversion of levulinic acid to optically active γ-valerolactone via asymmetric hydrogenation reaction.

Legal Information

Sold in collaboration with Takasago for research purposes only. JP Registration No. 3148136

SEGPHOS is a registered trademark of Takasago Intl. Corp.

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable