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Assay
97%
mp
52-56 °C (lit.)
SMILES string
[O-][N+](=O)c1ccnc(Cl)c1
InChI
1S/C5H3ClN2O2/c6-5-3-4(8(9)10)1-2-7-5/h1-3H
InChI key
LIEPVGBDUYKPLC-UHFFFAOYSA-N
Related Categories
Application
2-Chloro-4-nitropyridine may be used to synthesize 2-chloro-4-ethoxypyridine and 4-thiophenoxypyridines.
Starting material used in a tetrabutylammonium salt denitration leading to fluoro-, hydroxy- and methoxypyridines.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Journal of medicinal chemistry, 23(12), 1376-1380 (1980-12-01)
Eight nitropyridinesulfonamides and pyridinesulfonamide N-oxides as their bioisosteres were prepared and evaluated for anticoccidial activity. Of these compounds, 2-, 4- and 5-nitropyridine-3-sulfonamides and pyridine-2- and -3-sulfonamide N-oxides were found to be active against Eimeria tenella. Thus, the relative positions, ortho
Organic letters, 7(4), 577-579 (2005-02-12)
An efficient method for the synthesis of fluoropyridines via the fluorodenitration reaction is reported. The reaction is mediated by tetrabutylammonium fluoride (TBAF) under mild conditions without undue regard to the presence of water. The fluorodenitration is general for 2- or
Stabilised 2, 3-Pyridyne Reactive Intermediates of Exceptional Dienophilicity.
European Journal of Organic Chemistry, 16, 3477-3483 (2004)
Diels?Alder cycloadditions of stabilised 2, 3-pyridynes.
Tetrahedron Letters, 42(4), 735-737 (2001)
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