46746
Polyglycolic acid
Synonym(s):
PGA, Poly(2-hydroxyacetic acid)
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description
inherent viscosity 1.2 dl/g
InChI
1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
InChI key
AEMRFAOFKBGASW-UHFFFAOYSA-N
Application
medical device
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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M A Tiunin et al.
Eksperimental'naia i klinicheskaia farmakologiia, 76(1), 3-6 (2013-03-07)
Technological parameters for the effective encapsulation of n-(1-phenethyl-4-piperidyl)propionanilide in poly(lactid-co-glycolide) (PLG) nanoparticles have been determined. Depending on the ratio of drug fractions adsorbed on the particle surface and associated with the polymer matrix, n-(1-phenethyl-4-piperidyl)propionanilide (200 microg/kg, i/m) loaded PLG nanospheres
Huaping Chen et al.
Biomaterials, 34(16), 4159-4172 (2013-03-14)
The absence of safe, efficient, cost-effective, and easily scalable delivery platforms is one of the most significant hurdles and critical issues that limit the bench to bedside translation of oligonucleotides-based therapeutics. Acid-labile materials are of special interest in developing nonviral
Daniel E Levin et al.
Methods in molecular biology (Clifton, N.J.), 1001, 299-309 (2013-03-16)
Here, we describe the use of a mouse model as a living bioreactor for the generation of tissue-engineered small intestine. Small intestine is harvested from donor mice with subsequent isolation of organoid units (a cluster of mesenchymal and epithelial cells).
Kevin S Tang et al.
Nanotechnology, 24(12), 125101-125101 (2013-03-06)
Magnetic PLGA nanoparticles are a significant advancement in the quest to translate MRI-based cell tracking to the clinic. The benefits of these types of particles are that they encapsulate large amounts of iron oxide nanocrystals within an FDA-approved polymer matrix
Seokkee Lee et al.
The Annals of thoracic surgery, 95(6), 1919-1923 (2013-04-30)
Various procedures have been performed to decrease the incidence of recurrent postoperative pneumothorax after thoracoscopic bullectomy. The purpose of this study was to determine the efficacy of a polyglycolic acid (PGA) sheet and pleural abrasion for prevention of recurrent postoperative
Articles
Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.
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