44162
1,3-Bis[bis(2-pyridylmethyl)amino]-2-propanol solution
≥97.0% (HPLC), 10% in isopropanol
Synonym(s):
2-Hydroxy-N,N,N′,N′-tetrakis(2-pyridylmethyl)-1,3-propanediamine
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About This Item
Empirical Formula (Hill Notation):
C27H30N6O
CAS Number:
Molecular Weight:
454.57
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
Assay
≥97.0% (HPLC)
concentration
10% in isopropanol
density
0.817 g/mL at 20 °C (lit.)
SMILES string
OC(CN(Cc1ccccn1)Cc2ccccn2)CN(Cc3ccccn3)Cc4ccccn4
Other Notes
Ligand forming dinuclear metal complexes for efficient RNA hydrolysis; structure of zinc complexes
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H. Adams et al.
J. Chem. Soc., Dalton Trans., 925-925 (2002)
A Ishikubo et al.
Nucleic acids symposium series, 34(34), 85-86 (1995-01-01)
Dinuclear Zn(II) and La(III) complexes with TPHP efficiently hydrolyze a dinucleotide, ApA, under mild conditions (TPHP = N, N, N', N'-tetrakis[(2-pyridyl)-methyl]-2-hydroxy-1,3-diaminopropane). [Zn2(TPHP)]3+ hydrolyzes ApA with an extremely high activity; The pseudo-first-order rate constant is 8.4 x 10(-4) h-1 at pH
M Yashiro et al.
Journal of biochemistry, 120(6), 1067-1069 (1996-12-01)
A dinuclear La3+ complex hydrolyzes the phosphodiester bond in diribonucleotides efficiently under mild conditions. The rate of hydrolysis is remarkably accelerated on the complex formation between La3+ and TPHP (TPHP = N,N,N',N'-tetrakis [(2-pyridyl)methyl]-2-hydroxy-1,3-diaminopropane), and the highest activity is attained when
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