407925

4-Chloro-3-nitrobenzoyl chloride

98%

• Linear Formula: ClC₆H₃(NO₂)COCl
• CAS Number: 38818-50-7
• Molecular Weight: 220.01
• EC Number: 254-133-6
• MDL number: MFCD00035743
• UNSPSC Code: 12352100
• PubChem Substance ID: 24865495

Properties

• Assay: 98%
• mp: 47-54 °C (lit.)
• functional group: acyl chloride; chloro; nitro
• SMILES string: [O-][N+](=O)c1cc(ccc1Cl)C(Cl)=O
• InChI: 1S/C7H3Cl2NO3/c8-5-2-1-4(7(9)11)3-6(5)10(12)13/h1-3H
• InChI key: IWLGXPWQZDOMSB-UHFFFAOYSA-N

Description

General description

4-Chloro-3-nitrobenzoyl chloride is an acid halide.

Application

4-Chloro-3-nitrobenzoyl chloride may be employed as acylation reagent for the Friedel-Crafts acylation of activated benzenes such as anisole, veratrole and 1,4-dimethoxybenzene. It may be employed for the synthesis of 4-chloro-4-methoxy-3-nitrobenzophenone. It may be employed as acylation reagent for the acylation reaction of the deactivated amines (2- aminopyrimidine, aminopyrazine).

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves