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Sigma-Aldrich

2,2,2-Trifluoroethanesulfonyl chloride

99%

Synonym(s):

Tresyl chloride

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About This Item

Linear Formula:
CF3CH2SO2Cl
CAS Number:
1648-99-3
Molecular Weight:
182.55
Beilstein:
1860983
EC Number:
216-713-7
MDL number:
MFCD00007458
UNSPSC Code:
12352101
PubChem Substance ID:
24859467
NACRES:
NA.22

Assay

99%

form

liquid

refractive index

n20/D 1.388 (lit.)

bp

140-141 °C (lit.)
64-67 °C/45 mmHg (lit.)

density

1.651 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

FC(F)(F)CS(Cl)(=O)=O

InChI

1S/C2H2ClF3O2S/c3-9(7,8)1-2(4,5)6/h1H2

InChI key

CXCHEKCRJQRVNG-UHFFFAOYSA-N

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Related Categories

accessory

Product No.
Description
Pricing

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

161.6 °F - closed cup

Flash Point(C)

72 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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T Hayakawa et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 73(2), 271-276 (2005-01-28)
The immobilization of cell-adhesive proteins onto titanium implants improves biological response at the implant-tissue interface. Previous studies demonstrated the easy and direct attachment of fibronectin onto titanium with the use of a 2,2,2-trifluoroethanesulfonyl chloride (tresyl chloride) activation technique. The present
C F Mandenius et al.
Analytical biochemistry, 137(1), 106-114 (1984-02-01)
Two methods for the chemical binding of biomolecules to silicon surfaces are described. The first method utilizes an alkyl silane and a nucleophilic reagent to join the biomolecule to the silicon surface; the second method involves crosslinking with glutaraldehyde in
Markus Gantert et al.
Pharmaceutical research, 26(3), 529-538 (2008-11-19)
The challenge in developing liposomes to be used in active drug targeting is to design a method that can be used for modifying liposomal membranes that is applicable for a number of different specific ligands. In this study, the post
Jie Mei et al.
Electrophoresis, 29(18), 3825-3833 (2008-08-30)
A novel covalent coupling method for coating of capillaries with liposomes has been developed, which includes three steps: (i) epoxy-diol coating, (ii) activation with 2,2,2-trifluoroethanesulfonyl chloride, and (iii) liposome coupling. The coating conditions, such as the reaction time and temperature
K Nakamura et al.
Journal of chromatography, 510, 101-113 (1990-06-27)
A new activated support TSK gel Tresyl-5PW was evaluated for the coupling of antibodies, which was found to occur easily under mild conditions with high yields. Optimum coupling conditions were a 2-h reaction at 25 degrees C in 1 M
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