AR

androgen receptor

Synonyms:

AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM

Species:

Human AR (367), Mouse Ar (11835), Rat Ar (24208), fruit fly ar (44503), Zebrafish ar (100005148), chicken AR (422165), dog AR (403588), domestic cat AR (101081787), domestic cat AR (751827), Horse AR (100033980) ...More

UniProtKB ID:

P10275, A2RUN2, B1AKD7, Q9UD95

Gene ID:

Human(367) Summary: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Mouse(11835) androgen receptor
Rat(24208) androgen receptor
fruit fly(44503) abdomen rotatum
Zebrafish(100005148) androgen receptor
chicken(422165) androgen receptor
dog(403588) androgen receptor
domestic cat(101081787) androgen receptor
domestic cat(751827) androgen receptor
Horse(100033980) androgen receptor
cow(280675) androgen receptor
sheep(443042) androgen receptor
Goat(100860827) androgen receptor
Domestic Rabbit(100009193) androgen receptor
domestic guinea pig(100726891) androgen receptor

Products (254)
Peer Reviewed Papers (9,430)

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Small Molecule - Activator

Product Number

Description

Species

E8750

α-Estradiol, powder, ≥98% (TLC),

Species

human, rat

N4128

19-Norethindrone, ≥98%, powder,

Species

human, rat

484431

Propylene glycol monomethyl ether acetate, ReagentPlus^®, ≥99.5%,

Species

human

R5010

Resveratrol, ≥99% (HPLC),

Species

human, rat, mouse

D4628

Diethylstilbestrol, ≥99% (HPLC),

Species

human, mouse, rat

Small Molecule - Agonist

Product Number

Description

Species

Y0001317

Testosterone enantate for system suitability, European Pharmacopoeia (EP) Reference Standard,

Species

human

Y0002163

Testosterone for ID and assay, CRS, European Pharmacopoeia (EP) Reference Standard,

Species

human

M-912

Methandienone solution, 1.0 mg/mL in 1,2-dimethoxyethane, ampule of 1 mL, certified reference material, Cerilliant^®,

Species

human

90151

17β-Hydroxy-17-methylandrosta-1,4-dien-3-one, analytical standard,

Species

human

Y0000548

Nandrolone decanoate for system suitability, European Pharmacopoeia (EP) Reference Standard,

Species

human

Small Molecule - Antagonist

Product Number

Description

Species

Y0001448

Bicalutamide for system suitability, European Pharmacopoeia (EP) Reference Standard,

Species

human

Y0000829

Nilutamide, European Pharmacopoeia (EP) Reference Standard,

Species

human

N8534

Nilutamide, solid,

Species

human

54752

Methyl 4-hydroxybenzoate, tested according to Ph. Eur.,

Species

rat

442842

Benzophenone, analytical standard,

Species

rat

Antibodies

Product Number

Description

Species Reactivity

Application

SAB5500006

Anti-Androgen Receptor antibody, Rabbit monoclonal, clone SP107, recombinant, expressed in proprietary host, affinity isolated antibody,

Species Reactivity

dog, human, mouse, pig, rat

Application

immunohistochemistry

AMAB91547

Monoclonal Anti-AR antibody produced in mouse, Prestige Antibodies^® Powered by Atlas Antibodies, clone CL9255, purified immunoglobulin, buffered aqueous glycerol solution,

Species Reactivity

human

Application

immunohistochemistry
western blot

WH0000367M1

Monoclonal Anti-AR antibody produced in mouse, clone 1G3, purified immunoglobulin, buffered aqueous solution,

Species Reactivity

human

Application

ELISA
immunohistochemistry
proximity ligation assay
western blot

SAB4501574

Anti-Androgen Receptor, N-Terminal antibody produced in rabbit, affinity isolated antibody,