1692505

Trimethoprim

United States Pharmacopeia (USP) Reference Standard

• Synonyma: 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine, NSC 106568
• Empirický vzorec (Hillův zápis): C₁₄H₁₈N₄O₃
• Číslo CAS: 738-70-5
• Molekulová hmotnost: 290.32
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329751414
• MDL number: MFCD00036761
• Beilstein/REAXYS Number: 625127

Vlastnosti

• grade: pharmaceutical primary standard
• agency: USP
• API family: trimethoprim
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC
• InChI: 1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)
• InChI key: IEDVJHCEMCRBQM-UHFFFAOYSA-N

Popis

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Primarily used as an antibacterial agent. Dihydrofolate reductase inhibitor with selectivity for the prokaryote enzyme.

Trimethoprim USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

• Trimethoprim Tablets
• Trimethoprim Sulfate
• Sulfamethoxazole and Trimethoprim Tablets
• Sulfamethoxazole and Trimethoprim Injection
• Sulfamethoxazole and Trimethoprim Oral Suspension
• Polymyxin B Sulfate and Trimethoprim Ophthalmic Solution

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Bezpečnostní informace

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H361d
• pcodes: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Skladovací třída: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable