SML2046

ARM390

≥98% (HPLC)

• Synonyma: AR-M 1000390, N,N-Diethyl-4-(phenyl-4-piperidinylidenemethyl)benzamide
• Empirický vzorec (Hillův zápis): C₂₃H₂₈N₂O
• Číslo CAS: 209808-01-5
• Molekulová hmotnost: 348.48
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Vlastnosti

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: O=C(C1=CC=C(C(C2=CC=CC=C2)=C3CCNCC3)C=C1)N(CC)CC
• InChI: 1S/C23H28N2O/c1-3-25(4-2)23(26)21-12-10-19(11-13-21)22(18-8-6-5-7-9-18)20-14-16-24-17-15-20/h5-13,24H,3-4,14-17H2,1-2H3
• InChI key: SMUGAZNLKPFBSB-UHFFFAOYSA-N

Popis

Biochem/physiol Actions

ARM390 in a δ-selective opioid receptor agonist derivative of SNC80. ARM390 leads to very low levels of receptor internalization, and does not induce acute desensitization of analgesic response compared to SNC80. ARM390 preferentially recruits arrestin 3 to the delta opioid receptor in mice.

low-internalizing δ opioid receptor agonist

Bezpečnostní informace

• Skladovací třída: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable