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SML0982

Astaxanthin

≥95% (HPLC), powder, PPARγ

Synonyma:

(3S,3′S)-3,3′-dihydroxy-β,β-Carotene-4,4′-dione, trans-Astaxanthin

pro zobrazení organizačních a smluvních cen.

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Vám/Skladová položkaDostupnostCena
50 mg
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
4 540,00 Kč

O této položce

Empirický vzorec (Hillův zápis):
C40H52O4
Číslo CAS:
472-61-7
Molekulová hmotnost:
596.84
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥95% (HPLC)
Form:
powder
Storage condition:
desiccated, protect from light

4 540,00 Kč

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Název produktu

Astaxanthin, ≥95% (HPLC)

Quality Segment

100

assay

≥95% (HPLC)

form

powder

storage condition

desiccated, protect from light

color

, pink to very dark purple

solubility

DMSO: 1 mg/mL (warmed)

storage temp.

−20°C

SMILES string

O[C@H]1CC(C(=C(C1=O)C)\C=C\C(=C\C=C\C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C2=C(C(=O)[C@H](CC2(C)C)O)C)\C)\C)(C)C

InChI

1S/C40H52O4/c1-27(17-13-19-29(3)21-23-33-31(5)37(43)35(41)25-39(33,7)8)15-11-12-16-28(2)18-14-20-30(4)22-24-34-32(6)38(44)36(42)26-40(34,9)10/h11-24,35-36,41-42H,25-26H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,27-15+,28-16+,29-19+,30-20+/t35-,36-/m0/s1

InChI key

MQZIGYBFDRPAKN-UWFIBFSHSA-N

General description

Astaxanthin (AST) is a red dietary carotenoid. It is mainly found in aquatic animals and microalgae, such as Haematococcus pluvialis and Chlorella zofingiensis.

Application

Astaxanthin has been used:
  • as an antioxidant to study its effect on Brachionus manjavacas (Rotifera) population growth
  • to study its effects on the treatment of diabetic retinopathy.
  • to investigate its role in restoring the expression of Nrf2 (nuclear factor erythroid 2 p45-related factor 2) and glutathione S-transferase P1 (GSTP1) through epigenetic modification in human prostate LNCaP cells.

Biochem/physiol Actions

Astaxanthin is a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity.
Astaxanthin is a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity. Astaxanthin protects against oxidative stress, inhibiting NF-KB, suppressing pro-inflammatory genes and suppressing production of pro-inflammatory compounds nitric oxide, prostaglandin E2, TNF-α, and interleukin-1β. Astaxanthin′s protection of cells from oxidative stress generated by TNF-α and palmitate has been shown to ameliorate insulin resistance. Astaxanthin has also been shown to be an inhibitor of PPARγ.
In vivo and in vitro studies propose that astaxanthin (AST) possesses health-promoting activities, signifying its potential use in the prevention of various diseases, such as cancers and Parkinson′s disease. Due to its bright red colour, AST has been used as a food colorant in animal feeds.

Other Notes

Light and air sensitive

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Tato položka
41659117751044200
Astaxanthin ≥95% (HPLC)

Sigma-Aldrich

SML0982

Astaxanthin

all-trans-Astaxanthin analytical standard

Supelco

41659

all-trans-Astaxanthin

Canthaxanthin ≥95.0% (HPLC)

Sigma-Aldrich

11775

Canthaxanthin

USP

USP

1044200

Astaxanthin (synthetic)

form

powder

form

-

form

powder or crystals

form

-

assay

≥95% (HPLC)

assay

≥97%

assay

≥95.0% (HPLC)

assay

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage condition

desiccated, protect from light

storage condition

-

storage condition

-

storage condition

-

solubility

DMSO: 1 mg/mL (warmed)

solubility

-

solubility

-

solubility

-

color

, pink to very dark purple

color

-

color

light red to dark brown

color

-

Skladovací třída

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Osvědčení o analýze (COA)

Lot/Batch Number

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Questions

1–3 of 3 Questions  

  1. How long will this product be usable from the Quality Release Date?

    1 answer

    1. This product is not assigned an expiration or retest date. Products that are robust in nature and extremely stable, in the original unopened container, are not assigned an expiration date or retest schedule. These products will have no dating reported on either the label or the Certificate of Analysis.

      Products that are not assigned an expiration or retest date are covered by a warranty period of 1 year from the date of product shipment.

      Full Product Dating Information may be reviewed at the link below: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/190/408/product-dating-information-ms.pdf

      Helpful?

  2. is monoester or diester astaxanthin?

    1 answer

    1. This product is a free form.

      Helpful?

  3. Is the Astaxanthin SML0982 in the 3S, 3'S conformation or is it a mix?

    1 answer

    1. Unfortunately, we do not determine the conformation of this product.

      Helpful?

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