SMB00172

Tephrosin

≥95% (LC/MS-ELSD)

• Synonyma: Deguelinol I, Hydroxydeguelin
• Empirický vzorec (Hillův zápis): C₂₃H₂₂O₇
• Číslo CAS: 76-80-2
• Molekulová hmotnost: 410.42
• NACRES: NA.25
• PubChem Substance ID: 329824838
• UNSPSC Code: 12352205
• MDL number: MFCD00238693

Vlastnosti

• assay: ≥95% (LC/MS-ELSD)
• form: solid
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: −20°C
• SMILES string: COc1cc2OC[C@H]3Oc4c(ccc5OC(C)(C)C=Cc45)C(=O)[C@@]3(O)c2cc1OC
• InChI: 1S/C23H22O7/c1-22(2)8-7-12-15(30-22)6-5-13-20(12)29-19-11-28-16-10-18(27-4)17(26-3)9-14(16)23(19,25)21(13)24/h5-10,19,25H,11H2,1-4H3/t19-,23-/m1/s1
• InChI key: AQBZCCQCDWNNJQ-AUSIDOKSSA-N

Popis

General description

Natural product derived from plant source.

Biochem/physiol Actions

Tephrosin is a plant-based rotenoid which has known anti-cancer properties. Tephrosin inhibited proliferation in A549 cancer cells in a dose-sependent manner. Tephrosin has been shown to induce capase-independent apoptosis, and internalization and degradation of inactivated EGFR and ErB2 in human colon cancer cells.

Bezpečnostní informace

• pictograms: GHS09
• signalword: Warning
• hcodes: H410
• pcodes: P273 - P501
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1
• Skladovací třída: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable