Unfortunately, we do not have any Protoporphyrin IX that is classified as non-animal origin.
P8293
Protoporphyrin IX
From Porcine, ≥95%, guanylyl cyclase activator, powder
Synonyma:
3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic acid, Kammerer’s porphyrin, Ooporphyrin
Přihlásit pro zobrazení organizačních a smluvních cen.
Vybrat velikost
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| Vám/Skladová položka | Dostupnost | Cena |
|---|---|---|
1 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 7 450,00 Kč |
O této položce
Empirický vzorec (Hillův zápis):
C34H34N4O4
Číslo CAS:
Molekulová hmotnost:
562.66
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
209-033-7
MDL number:
Beilstein/REAXYS Number:
380795
Form:
powder
Assay:
≥95%
Solubility:
DMF: methanol (1:1): soluble-10 mg/mL, dark red-brown
Biological source:
Porcine
7 450,00 Kč
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
Technický servis
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Dovolte nám, abychom vám pomohliNázev produktu
Protoporphyrin IX, ≥95%
biological source
Porcine
Quality Segment
assay
≥95%
form
powder
solubility
DMF: methanol (1:1): soluble-10 mg/mL, dark red-brown
fluorescence
λex 402 nm; λem 625 nm (bound to HRP), λex 409 nm; λem 633 nm
storage temp.
2-8°C
SMILES string
Cc1c(CCC(O)=O)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(C)c5C=C)c(C)c4C=C)c(C)c3CCC(O)=O
InChI
1S/C34H34N4O4/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25/h7-8,13-16,35,38H,1-2,9-12H2,3-6H3,(H,39,40)(H,41,42)/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-
InChI key
KSFOVUSSGSKXFI-UJJXFSCMSA-N
General description
Protoporphyrin IX imparts red color to heme and is the major porphyrin in blood. It is synthesized from protoporphyrinogen IX in the presence of protoporphyrinogen IX oxidase.
Protoporphyrin IX belongs to the porphyrin family, which are a class of tetrapyrroles. It is the iron-free form of hemin and amphiphilic in nature. It is the precursor of heme in its biosynthetic pathway.
Application
Activates soluble guanylyl cyclase.
Protoporphyrin IX has been used:
- as a standard in protoporphyrin assays[1]
- in fluorescence spectra analysis
- to treat cells in cell culture to study heme-mediated ferroportin 1 transcription
Biochem/physiol Actions
Protoporphyrin IX levels are elevated in tumor cells due to metabolism anomalies compared to normal cells.
Protoporphyrin IX penetrates human erythrocytes and aids the release of oxygen from them. It forms complexes with myoglobin and hemoglobin. It is a photosensitizer used in the photodynamic therapy of cancer.
1 of 1
Tato položka | |||
|---|---|---|---|
| solubility DMF: methanol (1:1): soluble-10 mg/mL, dark red-brown | solubility - | solubility - | solubility - |
| assay ≥95% | assay ≥90% (HPLC) | assay 90% | assay ≥92% (HPLC) |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| biological source Porcine | biological source - | biological source - | biological source - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - | storage temp. room temp |
| form powder | form powder | form solid | form powder |
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Skladovací třída
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Dear Sir / Madam, Is any of your Protoporphyrin IX / Hemine products (sodium salt, ester, free acid) be classified as non-animal origin / sufficiently processed proven by analytical testing to show that the products are free of biological contaminants?
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