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C8707

Sigma-Aldrich

Cystamine dihydrochloride

BioXtra

Synonyma:

2,2′-Diaminodiethyl disulfide dihydrochloride, 2,2′-Dithiobis(ethylamine) dihydrochloride, Decarboxycystine dihydrochloride

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About This Item

Lineární vzorec:
NH2CH2CH2SSCH2CH2NH2 · 2HCl
Číslo CAS:
56-17-7
Molekulová hmotnost:
225.20
Beilstein/REAXYS Number:
3616850
EC Number:
200-260-7
MDL number:
MFCD00012905
UNSPSC Code:
12352200
PubChem Substance ID:
24893096
NACRES:
NA.25

product line

BioXtra

assay

≥98% (TLC)

form

powder

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.1%

mp

217-220 °C (dec.) (lit.)

solubility

H2O: 0.1 M, clear, colorless to light yellow

anion traces

sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.02%
Cu: ≤0.0005%
Fe: ≤0.001%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

Cl[H].Cl[H].NCCSSCCN

InChI

1S/C4H12N2S2.2ClH/c5-1-3-7-8-4-2-6;;/h1-6H2;2*1H

InChI key

YUFRRMZSSPQMOS-UHFFFAOYSA-N

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Související kategorie

Application

Cystamine dihydrochloride is a useful reagent to derivatize various polymer monoliths for hydrophilic interaction liquid chromatography; as a crosslinking agent in the development of polymer hydrogels; and as a functional group in nanoparticles developed for siRNA and DNA delivery.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Osvědčení o analýze (COA)

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Chemistry (Weinheim an der Bergstrasse, Germany), 18(11), 3185-3192 (2012-02-22)
Autofluorescent microcapsules were assembled by covalent cross-linking of polysaccharide alginate dialdehyde (ADA) derivative and cystamine dihydrochloride (CM) through a layer-by-layer (LBL) technique. The formulated Schiff base and disulfide bonds render capsules with pH- and redox-responsive properties for pinpointed intracellular delivery
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Journal of chromatography. A, 1342, 70-77 (2014-04-15)
A polyhedral oligomeric silsesquioxane (POSS) hybrid monolith was simply prepared by using octaglycidyldimethylsilyl POSS (POSS-epoxy) and cystamine dihydrochloride as monomers via ring-opening polymerization. The effects of composition of prepolymerization solution and polycondensation temperature on the morphology and permeability of monolithic
Jie Gao et al.
Langmuir : the ACS journal of surfaces and colloids, 28(9), 4464-4471 (2012-01-27)
Gold nanoparticles (GNPs) are attractive alternative optical probes and good biocompatible materials due to their special physical and chemical properties. However, GNPs have a tendency to aggregate particularly in the presence of high salts and certain biological molecules such as
Yasue Ishii-Osai et al.
Journal of dermatological science, 67(1), 51-60 (2012-05-25)
N-propionyl-4-S-cysteaminylphenol (NPr-4-S-CAP) is selectively incorporated into melanoma cells and degrades them. However, it remains unclear whether NPr-4-S-CAP can induce cell death associated with the induction of host immune responses and tumor suppression in vivo. To examine the molecular mechanism of
Shosuke Ito et al.
Biochemical pharmacology, 84(5), 646-653 (2012-06-26)
Metastatic melanoma is resistant to conventional therapies. N-propionyl-4-S-cysteaminylphenol (NPrCAP), an N-protected sulfur-amine analog of tyrosine, is a good substrate for tyrosinase and is selectively incorporated into melanoma cells, causing cytotoxicity in vitro and in vivo. We have recently shown that
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