N8280

Naproxen

• Synonyma: (S)-(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid, (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid
• Lineární vzorec: CH₃OC₁₀H₆CH(CH₃)CO₂H
• Číslo CAS: 22204-53-1
• Molekulová hmotnost: 230.26
• UNSPSC Code: 12352200
• NACRES: NA.21
• PubChem Substance ID: 24897861
• EC Number: 244-838-7
• Beilstein/REAXYS Number: 3591068
• MDL number: MFCD00010500
• Assay: ≥90% (HPLC)
• Form: powder

Vlastnosti

• Quality Segment: 200
• assay: ≥90% (HPLC)
• form: powder
• loss: ≤1.0% loss on drying
• color: white to off-white
• mp: 152-154 °C (lit.)
• cation traces: heavy metals: ≤0.002%
• application(s): pharmaceutical (small molecule)
• SMILES string: COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O
• InChI: 1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
• InChI key: CMWTZPSULFXXJA-VIFPVBQESA-N
• Gene Information: human ... MAPK14(1432), PTGS1(5742), PTGS2(5743) ; rat ... Alox5(25290), Ptgs1(24693)

Popis

Biochem/physiol Actions

Non-selective cyclooxygenase (COX-1 and COX-2) inhibitor.

Bezpečnostní informace

• Piktogramy: GHS08,GHS07,GHS09
• Výstražné slovo: Warning
• Kódy nebezpečí: H302,H315,H319,H335,H361fd,H411
• Bezpečnostní pokyny: P202 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
• Cílové orgány: Respiratory system
• Skladovací třída: 11 - Combustible Solids