938963

Potassium tert-butoxide ChemBeads

solid

• Synonyma: Potassium tert-butylate, Potassium t-butoxide
• Empirický vzorec (Hillův zápis): KOC₄H₉
• Číslo CAS: 865-47-4
• Molekulová hmotnost: 112.21
• UNSPSC Code: 12352100
• MDL number: MFCD00012162
• NACRES: NA.21
• Form: solid

Vlastnosti

• Název produktu: Potassium tert-butoxide ChemBeads,
• description: Reagent Type-Organic Salt
• Quality Segment: 100
• product line: ChemBeads
• form: solid
• composition: wt% loading of base, 14-16 wt. %
• reaction suitability: core: potassium
• greener alternative product characteristics: Catalysis; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• greener alternative category: Aligned
• SMILES string: [K+].CC(C)(C)[O-]
• InChI: 1S/C4H9O.K/c1-4(2,3)5;/h1-3H3;/q-1;+1
• InChI key: LPNYRYFBWFDTMA-UHFFFAOYSA-N

Popis

General description

Potassium tert-butoxide is a strong alkoxide base, it can deprotonate carbon and other Brφnsted acids. It is a relatively poor nucleophile.

Application

Potassium tert-butoxide has been used as a strong base in the enantioselective synthesis of amines by transfer hydrogenation of N-(tertbutylsulfinyl)imines. It can also be used: To synthesize aliphatic and aromatic amides from corresponding esters and amines. As a base in the intramolecular cyclization of aryl ethers, amines, and amides. As a catalyst to prepare styrene derivatives from aryl halides and alkenes by Mizoroki-Heck reaction.
For general uses, product is also available in powdered form (156671)

Features and Benefits

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is an environmentally benign and has been enhanced for catalytic efficiency. Click here for more information.

Other Notes

High-Throughput Reaction Screening with Nanomoles of Solid Reagents Coated on Glass Beads

Versatile Methods to Dispense Sub-Milligram Quantities of Solids using Chemical Coated Beads for High-Throughput Experimentation

ChemBead Enabled High-Throughput Cross-Electrophile Coupling Reveals a New Complementary Ligand

Bezpečnostní informace

• pictograms: GHS02,GHS05
• signalword: Danger
• hcodes: H228,H252,H314
• pcodes: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 2 - Skin Corr. 1A
• supp_hazards: EUH014
• Skladovací třída: 4.2 - Pyrophoric and self-heating hazardous materials
• wgk: WGK 3