91741

Trimethylsilyl trifluoromethanesulfonate

purum, ≥98.0% (T)

• Synonyma: TMS triflate, TMSOTf, Trifluoromethanesulfonic acid trimethylsilylester
• Lineární vzorec: CF₃SO₃Si(CH₃)₃
• Číslo CAS: 27607-77-8
• Molekulová hmotnost: 222.26
• UNSPSC Code: 12352101
• NACRES: NA.22
• PubChem Substance ID: 329770075
• EC Number: 248-565-4
• Beilstein/REAXYS Number: 1868911
• MDL number: MFCD00000406
• Assay: ≥98.0% (T)
• Form: liquid

Vlastnosti

• grade: purum
• Quality Segment: 200
• assay: ≥98.0% (T)
• form: liquid
• reaction suitability: reactivity: alcohol reactive, reagent type: protection reagent
• refractive index: n20/D 1.36 (lit.)
• bp: 77 °C/80 mmHg (lit.)
• density: 1.228 g/mL at 25 °C (lit.)
• functional group: fluoro, triflate
• SMILES string: C[Si](C)(C)OS(=O)(=O)C(F)(F)F
• InChI: 1S/C4H9F3O3SSi/c1-12(2,3)10-11(8,9)4(5,6)7/h1-3H3
• InChI key: FTVLMFQEYACZNP-UHFFFAOYSA-N

Popis

Application

Trimethylsilyl trifluoromethanesulfonate may be used to catalyze:

• Allylation of acetals to form homoallyl ethers.
• Synthesis of 1,2-trans-glycosides.
• Conversion of alcohols to esters.
• Aminomethylation of silyl enol ethers with aminomethyl alkyl ethers.
• Glycosidation of (+)-4-demethoxyanthracyclinones.

Other Notes

Efficient silylating agent and strong Lewis acid catalyst ; Review

Bezpečnostní informace

• pictograms: GHS02,GHS05
• signalword: Danger
• hcodes: H226,H314
• pcodes: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Flam. Liq. 3 - Skin Corr. 1B
• supp_hazards: EUH014
• Skladovací třída: 3 - Flammable liquids
• wgk: WGK 3
• flash_point_f: 77.0 °F - closed cup
• flash_point_c: 25 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter