242284

Aniline

ACS reagent grade, ≥99.5%, liquid, suitable for analytical testing

• Synonyma: Aminobenzene, Benzenamine
• Lineární vzorec: C₆H₅NH₂
• Číslo CAS: 62-53-3
• Molekulová hmotnost: 93.13
• NACRES: NA.21
• PubChem Substance ID: 24854547
• eCl@ss: 39030407
• UNSPSC Code: 12352100
• EC Number: 200-539-3
• MDL number: MFCD00007629
• Beilstein/REAXYS Number: 605631
• Assay: ≥99.5%
• Grade: ACS reagent
• Bp: 184 °C (lit.)
• Vapor pressure: 0.7 mmHg ( 25 °C)

Vlastnosti

• Název produktu: Aniline, ACS reagent, ≥99.5%
• material: red polypropylene cap
• Quality Segment: 200
• grade: ACS reagent
• vapor density: 3.22 (185 °C, vs air)
• vapor pressure: 0.7 mmHg ( 25 °C)
• assay: ≥99.5%
• form: liquid
• autoignition temp.: 1139 °F
• expl. lim.: 11 %
• dilution: (for analytical testing)
• impurities: Hydrocarbons, passes test, Nitrobenzene, passes test (lim. ~0.001%), ≤0.01% chlorobenzene
• ign. residue: ≤0.005%
• refractive index: n20/D 1.586 (lit.)
• bp: 184 °C (lit.)
• mp: −6 °C (lit.)
• solubility: water: soluble
• density: 1.022 g/mL at 25 °C (lit.)
• storage temp.: room temp
• SMILES string: Nc1ccccc1
• InChI: 1S/C6H7N/c7-6-4-2-1-3-5-6/h1-5H,7H2
• InChI key: PAYRUJLWNCNPSJ-UHFFFAOYSA-N

Popis

General description

Material darkens in storage to reddish-brown with no loss in purity.

Application

Aniline is an aromatic primary amine that may be used as a reactant in the synthesis of organic intermediates such as 3-chloro-N-phenyl-pyridin-2-amine, (Z)-methyl 3-(phenylamino)but-2-enoate, 2-iodo-N-phenylbenzamide, 2,4-dichloroquinoline and N-(2-propynyl)aniline.

Biochem/physiol Actions

The acute toxicity of aniline involves its activation in vivo to 4-hydroxyaniline and the formation of adducts with hemoglobin. In erythrocytes, this is associated with the release of iron and the accumulation of methemoglobin and the development of hemolytic anemia and inflammation of the spleen. Tumor formation is often observed in the spleen on prolonged administration.

Bezpečnostní informace

• pictograms: GHS06,GHS08,GHS05,GHS09
• signalword: Danger
• hcodes: H301 + H311 + H331,H317,H318,H341,H351,H372,H410
• pcodes: P273 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1 - STOT RE 1
• target_organs: Blood
• Skladovací třída: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: 158.0 °F - closed cup
• flash_point_c: 70 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter