MAB2146
Anti-ICAM-1 Antibody, clone P2A4
clone P2A4, Chemicon®, from mouse
Synonyma:
CD54
Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Doporučené produkty
biological source
mouse
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
P2A4, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ICAM1(3383)
Související kategorie
Specificity
Human ICAM-1
Immunogen
IL-1beta activated HUVEC (human)
Application
Anti-ICAM-1 Antibody, clone P2A4 is an antibody against ICAM-1 for use in ELISA, FC, IP, IC, IH.
Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue
Immunocytochemistry: for use on B cells, PBL, T cells
Immunoprecipitation
FACS
ELISA
Inhibits ICAM-1 dependent adhesive interactions
Optimal working dilutions must be determined by end user.
Immunocytochemistry: for use on B cells, PBL, T cells
Immunoprecipitation
FACS
ELISA
Inhibits ICAM-1 dependent adhesive interactions
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Adhesion (CAMs)
Adhesion (CAMs)
Physical form
Format: Purified
Nonsterile liquid contains 0.2M phosphate buffer, 0.25M sodium chloride, and 0.1% sodium azide. Filtered through a 0.45 micron membrane filter.
Storage and Stability
Maintain at +2-8°C.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Activation of vascular endothelial cells (ECs) plays an important role in atherogenesis and plaque instability. Lipoproteins containing apolipoprotein CIII (apoCIII) predict coronary heart disease (CHD). We recently reported that apoCIII has a proinflammatory effect on human monocytes. In this study
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Arteriosclerosis, thrombosis, and vascular biology, 24(12), 2263-2270 (2004-10-02)
Vascular smooth muscle cells (VSMCs) may regulate monocyte functions within atherosclerotic lesions. We investigated the impact of VSMC/monocyte interactions on monocyte apoptosis and scavenger receptor CD36 expression, key events related to monocyte survival and differentiation. Serum deprivation significantly increased THP-1
E Pluskota et al.
The Journal of biological chemistry, 275(39), 30029-30036 (2000-06-24)
Intercellular adhesion molecule-1 (ICAM-1) binds to the plasma protein fibrinogen (Fg) to mediate leukocyte/endothelial cell interactions. In our studies, the ligation of Fg to ICAM-1 on tumor necrosis factor-alpha-stimulated endothelial cells resulted in the tyrosine phosphorylation of Src homology domain
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