625625 is a research use reagent that is not provided sterile. It will be up to the user to determine its suitability for in vivo use.
625625
Trehalose, Dihydrate
Non-reducing disaccharide which yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro.
Synonyma:
Trehalose, Dihydrate, 1-O-α-D-Glucopyranosyl-α-D-glucopyranoside
Přihlásit pro zobrazení organizačních a smluvních cen.
Vybrat velikost
Změnit zobrazení
| Vám/Skladová položka | Dostupnost | Cena |
|---|---|---|
50 g | Očekávané datum odeslání09. června 2026odAreál Kühne+Nagel spol. s r.o. | 3 960,00 Kč |
1 kg | Očekávané datum odeslání09. června 2026odAreál Kühne+Nagel spol. s r.o. | 54 000,00 Kč |
O této položce
Empirický vzorec (Hillův zápis):
C12H22O11 · 2H2O
Číslo CAS:
Molekulová hmotnost:
378.33
UNSPSC Code:
12352201
NACRES:
NA.79
MDL number:
3 960,00 Kč
Očekávané datum odeslání09. června 2026podrobné informace
Technický servis
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Merck USA index - 14, 9580
Quality Segment
assay
≥97.5% (by Assay)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
water: 100 mg/mL
cation traces
Fe: <5 ppm, heavy metals: <10 ppm
shipped in
ambient
storage temp.
15-25°C
SMILES string
O1[C@@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO.O.O
InChI
1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1
InChI key
DPVHGFAJLZWDOC-PVXXTIHASA-N
General description
Non-reducing disaccharide that yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration. Reported to prevent myoglobin collapse and preserve its internal mobility.
Non-reducing disaccharide which yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration.
Other Notes
Sarkar, S., et al. 2007. J. Biol. Chem. In press.
Tanaka, M., et al. 2004. Nat. Med.10, 148.
Sastry, G.M. and Agmon, N. 1997. Biochemistry 36, 7097.
Tanaka, M., et al. 2004. Nat. Med.10, 148.
Sastry, G.M. and Agmon, N. 1997. Biochemistry 36, 7097.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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Tato položka | |||
|---|---|---|---|
| assay ≥97.5% (by Assay) | assay ≥99.0% (HPLC) | assay ≥99% | assay - |
| solubility water: 100 mg/mL | solubility H2O: 0.1 g/mL, clear, colorless | solubility H2O: 50 mg/mL | solubility - |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 500 |
| form solid | form powder | form powder | form solid |
| storage temp. 15-25°C | storage temp. - | storage temp. - | storage temp. no temp limit |
| cation traces Fe: <5 ppm, heavy metals: <10 ppm | cation traces As: ≤0.1 mg/kg, Ca: ≤200 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤10 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤10 mg/kg | cation traces - | cation traces - |
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Skladovací třída
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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