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480030

NEMO-Binding Domain Binding Peptide, Cell-Permeable, Negative Control

A cell-permeable Antennapedia-NBD mutated fusion peptide analog of NEMO-Binding Domain Binding Peptide that serves as a negative control.

Synonyma:

NEMO-Binding Domain Binding Peptide, Cell-Permeable, Negative Control, DRQIKIWFQNRRMKWKK-TALDASALQTE, NBD-Binding Peptide, Cell-Permeable, Negative Control

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Změnit zobrazení
Vám/Skladová položkaDostupnostCena
500 μg

Očekávané datum odeslání05. srpna 2026odAreál Kühne+Nagel spol. s r.o.

7 450,00 Kč

O této položce

Empirický vzorec (Hillův zápis):
C154H249N47O42S
Molekulová hmotnost:
3462.98
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥95% (HPLC)
Form:
lyophilized solid
Storage condition:
OK to freeze, desiccated (hygroscopic)

7 450,00 Kč

Očekávané datum odeslání05. srpna 2026podrobné informace

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Quality Segment

100

assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic)

color

off-white

solubility

DMSO: 50 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

A cell-permeable Antennapedia-NBD mutated (Trp739 and Trp741 replaced with Ala) fusion peptide analog of NEMO-Binding Domain Binding Peptide (Cat. No. 480025) that serves as a negative control. Shown to be defective in binding to NEMO. Does not affect the TNF-α-induced phosphorylation of c-Jun and DNA binding of the transcription factor Oct-1.
A cell-permeable, Antennapedia-NBD mutated (Trp739 → Ala and Trp741 → Ala) fusion peptide analog of NEMO-Binding Domain Binding peptide (Cat. No. 480025) that serves as a negative control. Reported to be defective in binding to NEMO. Does not affect the TNF-α-induced phosphorylation of c-Jun or DNA binding of the transcription factor Oct-1.

Biochem/physiol Actions

Cell permeable: yes
Primary Target
Negative control defective in binding to NEMO
Product does not compete with ATP.
Reversible: no

Packaging

Packaged under inert gas

Other Notes

H₂N-Asp-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Thr-Ala-Leu-Asp-Ala-Ser-Ala-Leu-Gln-Thr-Glu-OH
Jimi, E., et al. 2004. Nat. Med., 10, 617.
May, M.J., et al. 2000. Science289, 1550.
This peptide will precipitate when added to tissue culture medium even at 100 µM concentrations; however, sufficient material will stay in solution to permeate cells.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Tato položka
197225196811208904
NEMO-Binding Domain Binding Peptide, Cell-Permeable, Negative Control A cell-permeable Antennapedia-NBD mutated fusion peptide analog of NEMO-Binding Domain Binding Peptide that serves as a negative control.

Sigma-Aldrich

480030

NEMO-Binding Domain Binding Peptide, Cell-Permeable, Negative Control

Bcl-2 Binding Peptide, Cell-Permeable, Negative Control A cell-permeable, mutated cpm-1285 peptide analog (Leu¹⁵¹ replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding.

Sigma-Aldrich

197225

Bcl-2 Binding Peptide, Cell-Permeable, Negative Control

Bax-Inhibiting Peptide, Negative Control A cell-permeable negative control of the Bax-Inhibiting Peptide, V5. Does not suppress Bax-mediated apoptosis (~200 µM).

Sigma-Aldrich

196811

Bax-Inhibiting Peptide, Negative Control

Calpastatin Peptide, Negative Control A scrambled peptide with an identical amino acid composition to that of Calpastatin Peptide. Useful as a negative control for Calpastatin Peptide.

Sigma-Aldrich

208904

Calpastatin Peptide, Negative Control

description

A cell-permeable Antennapedia-NBD mutated fusion peptide analog of NEMO-Binding Domain Binding Peptide that serves as a negative control.

description

A cell-permeable, mutated cpm-1285 peptide analog (Leu¹⁵¹ replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding.

description

A cell-permeable negative control of the Bax-Inhibiting Peptide, V5. Does not suppress Bax-mediated apoptosis (~200 µM).

description

A scrambled peptide with an identical amino acid composition to that of Calpastatin Peptide. Useful as a negative control for Calpastatin Peptide.

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

form

lyophilized solid

form

solid

form

lyophilized solid

form

lyophilized solid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage condition

OK to freeze, desiccated (hygroscopic)

storage condition

OK to freeze, desiccated (hygroscopic)

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

storage condition

OK to freeze, desiccated (hygroscopic)

Skladovací třída

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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