427572

Bovine Lactosyl Ceramide

≥98% (TLC), solid, glycosphingolipid precursor, Calbiochem^®

• Synonyma: Lactosyl Ceramide, Bovine, Galβ,1,4Glc-Cer, LacCer, LC, LC, Galβ,1,4Glc-Cer, LacCer
• Empirický vzorec (Hillův zápis): C₅₃H₁₀₁NO₁₃
• Číslo CAS: 4682-48-8
• Molekulová hmotnost: 960.37
• UNSPSC Code: 12352211
• NACRES: NA.77
• MDL number: MFCD00133445
• Assay: ≥98% (TLC)
• Form: solid
• Storage condition: OK to freeze

Vlastnosti

• Název produktu: Lactosyl Ceramide, Bovine, A neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL.
• Quality Segment: 100
• description: RTECS - FK1000000
• assay: ≥98% (TLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: colorless
• solubility: ethanol: 1 mM, methanol: 1 mM
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: N(C(C(O)\C=C\CCCCCCCCCCCCC)CO[C@@H]1O[C@@H]([C@@H]([C@@H]([C@H]1O)O)OC2O[C@@H]([C@@H]([C@@H]([C@H]2O)O)O)CO)CO)C(=O)CCCCCCCCCCCCCCCCC
• InChI: 1S/C48H91NO13/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-40(53)49-36(37(52)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2)35-59-47-45(58)43(56)46(39(34-51)61-47)62-48-44(57)42(55)41(54)38(33-50)60-48/h29,31,36-39,41-48,50-52,54-58H,3-28,30,32-35H2,1-2H3,(H,49,53)/b31-29+/t36?,37?,38-,39-,41+,42+,43-,44-,45-,46+,47-,48?/m1/s1
• InChI key: VOZHMDQUIRUFQW-AIRKALMMSA-N

Popis

General description

A neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of p44 MAP kinase. Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase, and c-fos expression in human aortic smooth muscle cells.

A neutral glycosphingolipid (GSL) which is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco- series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of p44 MAP kinase. Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase and c-fos expression in human aortic smooth muscle cells.



Molecular weight: 960.4 (based on tricosanyl -23:0)

M.W. 960.4 (based on tricosanoyl - 23:0).

Biochem/physiol Actions

Cell permeable: no

Primary Target
A neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Other Notes

Bhunia, A.K., et al. 1997. J. Biol. Chem.272, 15642.
Bhunia, A.K., et al. 1996. J. Biol. Chem.271, 10660.
Zacharias, C., et al. 1994. J. Biol. Chem.269, 13313.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

Bezpečnostní informace

• Skladovací třída: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable