810258E

C11 TopFluor^™ GM3

Avanti Research^™ - A Croda Brand

• Synonyma: C11 TopFluor GM3 Ganglioside (ammonium salt)
• Empirický vzorec (Hillův zápis): C₆₅H₁₁₀BF₂N₅O₂₁
• Číslo CAS: 2260795-48-8
• Molekulová hmotnost: 1346.40
• MDL number: MFCD00066515
• NACRES: NA.25
• UNSPSC Code: 12352211

Vlastnosti

• Název produktu: C11 TopFluor^™ GM3, Avanti Research^™ - A Croda Brand 810258E, ethanol solution
• assay: >99% (TLC)
• form: ethanol solution
• packaging: pkg of 1 × 1 mL (810258E-100ug)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 810258E
• concentration: 0.1 mg/mL (810258E-100ug)
• shipped in: dry ice
• storage temp.: −20°C

Popis

General description

C11 TopFluor^™ GM3 is a fluorescent analog of ganglioside GM3 (Siaa2-3Galb1-4Glcb1-1Cer).

Application

C11 TopFluor^™ GM3 has been used to visualize GM3 present in UGCG-KO1.3 cells by immunofluorescence microscopy.

Biochem/physiol Actions

Gangliosides function as modulators in regulating various receptor functions, involved in transmembrane signaling. GM3 plays an important role as a metabolic precursor for the formation of more complex gangliosides. It comprises between 80% and 90% of total ganglioside content in liver and adipose tissue, respectively. Additionally, GM3 is known to promote the subcellular redistribution of major caveolin enriched microdomain (CEM) components coordinating signal transduction. The increased levels of ganglioside GM3 in serum is reported in hyperlipidaemic, hyperglycaemic and type 2 diabetic patients.

Packaging

5 mL Amber Glass Screw Cap Vial (810258E-100ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

TopFluor is a trademark of Avanti Polar Lipids, LLC

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.

Bezpečnostní informace

• Piktogramy: GHS02,GHS07
• Výstražné slovo: Danger
• Kódy nebezpečí: H225,H319
• Bezpečnostní pokyny: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2
• Skladovací třída: 3 - Flammable liquids
• Co se děje?: WGK 1
• Bod vzplanutí (°F): 55.4 °F - closed cup
• Bod vzplanutí (°C): 13.0 °C - closed cup