934305

Pomalidomide-PEG1-C2-amine HCl

≥95.0%

• Synonyma: 4-[[2-(2-Aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
• Empirický vzorec (Hillův zápis): C₁₇H₂₀N₄O₅ · xHCl
• Číslo CAS: 2154342-56-8
• Molekulová hmotnost: 360.36 (free base basis)
• UNSPSC Code: 12352116
• NACRES: NA.21
• MDL number: MFCD32666562
• Assay: ≥95.0%
• Form: powder or crystals

Vlastnosti

• ligand: pomalidomide
• Quality Segment: 100
• assay: ≥95.0%
• form: powder or crystals
• color: faint yellow to dark yellow
• storage temp.: 2-8°C
• SMILES string: Cl.O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCOCCN)C3C2=O)CC1
• InChI: 1S/C17H20N4O5.ClH/c18-6-8-26-9-7-19-11-3-1-2-10-14(11)17(25)21(16(10)24)12-4-5-13(22)20-15(12)23;/h1-3,12,19H,4-9,18H2,(H,20,22,23);1H
• InChI key: LQYLHZFKGOZTOH-UHFFFAOYSA-N

Popis

Application

Technology Spotlight:

Degrader Building Blocks for Targeted Protein Degradation

Protein Degrader Building Blocks

Other Notes

Targeted Protein Degradation by Small Molecules

Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERG

Small-Molecule PROTACS: New Approaches to Protein Degradation

Targeted Protein Degradation: from Chemical Biology to Drug Discovery

Impact of linker length on the activity of PROTACs

Legal Information

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Bezpečnostní informace

• Piktogramy: GHS08
• Výstražné slovo: Danger
• Kódy nebezpečí: H360D
• Bezpečnostní pokyny: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B
• Skladovací třída: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Bod vzplanutí (°F): Not applicable
• Bod vzplanutí (°C): Not applicable