640042

4-Amino-1-Boc-piperidine

97%

• Synonyma: 1-Boc-4-piperidinamine, tert-Butyl 4-amino-1-piperidinecarboxylate
• Empirický vzorec (Hillův zápis): C₁₀H₂₀N₂O₂
• Číslo CAS: 87120-72-7
• Molekulová hmotnost: 200.28
• NACRES: NA.22
• PubChem Substance ID: 24883073
• UNSPSC Code: 12352100
• MDL number: MFCD01076201
• Assay: 97%
• Form: solid

Vlastnosti

• Quality Segment: 100
• assay: 97%
• form: solid
• SMILES string: CC(C)(C)OC(=O)N1CCC(N)CC1
• InChI: 1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-8(11)5-7-12/h8H,4-7,11H2,1-3H3
• InChI key: LZRDHSFPLUWYAX-UHFFFAOYSA-N

Popis

Application

Employed in a microwave-assisted solid-phase synthesis of N-substituted piperidines via direct annulation of primary amines with resin-bound dimesylates.

4-Amino-1-Boc-piperidine can be used:

• as a starting material in the synthesis of N-(3-(4-hydroxyphenyl)-propenoyl)-amino acid tryptamides, which can act as silent information regulator human type 2 (SIRT2) inhibitors
• to synthesize piperidine-substituted triazine derivativesand piperidinylamino-diarylpyrimidine (pDAPY) derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors (HIV-1 NNRTIs)

Bezpečnostní informace

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H315,H318,H335
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Skladovací třída: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves