128910

N,O-Bis(trimethylsilyl)acetamide

synthesis grade, ≥95%

• Synonyma: BSA
• Lineární vzorec: CH₃C[=NSi(CH₃)₃]OSi(CH₃)₃
• Číslo CAS: 10416-59-8
• Molekulová hmotnost: 203.43
• UNSPSC Code: 12352103
• NACRES: NA.22
• PubChem Substance ID: 24847878
• EC Number: 233-892-7
• Beilstein/REAXYS Number: 1306669
• MDL number: MFCD00008270
• Assay: ≥95%
• Form: liquid

Vlastnosti

• grade: synthesis grade
• Quality Segment: 100
• assay: ≥95%
• form: liquid
• reaction suitability: reactivity: alcohol reactive, reactivity: amine reactive, reagent type: protection reagent
• refractive index: n20/D 1.417 (lit.)
• bp: 71-73 °C/35 mmHg (lit.)
• density: 0.832 g/mL at 20 °C (lit.)
• functional group: amine
• SMILES string: C\C(O[Si](C)(C)C)=N/[Si](C)(C)C
• InChI: 1S/C8H21NOSi2/c1-8(9-11(2,3)4)10-12(5,6)7/h1-7H3/b9-8+
• InChI key: SIOVKLKJSOKLIF-CMDGGOBGSA-N

Popis

General description

N,O-Bis(trimethylsilyl)acetamide(BSA) is a powerful silylating agent for the protection of amides, amines, alcohols, carboxylic acids, enols and phenols. It can also be used as a Bronsted base precursor in Tsuji–Trost reactions. Additionally, it can be used to activate different functional groups during the production of nucleosides, peptides, and heterocycles.

Application

Derivatization reagent for GC-MS analysis of phenolic acids in fruits.

Reagent for the regioselective desulfation of polysaccharide sulfates. Also used to prepare trimethylsilyl ethers of carbohydrates and alcohols.

Features and Benefits

BSA is good moisture absorbent.

Bezpečnostní informace

• Piktogramy: GHS02,GHS05,GHS07
• Výstražné slovo: Danger
• Kódy nebezpečí: H226,H302,H314
• Bezpečnostní pokyny: P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Flam. Liq. 3 - Skin Corr. 1B
• supp_hazards: EUH014
• Skladovací třída: 3 - Flammable liquids
• Co se děje?: WGK 3
• Bod vzplanutí (°F): 111.2 °F - closed cup
• Bod vzplanutí (°C): 44 °C - closed cup
• PPE (osobní ochranné prostředky): Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges