SML2753
UCSF4226
≥98% (HPLC)
Synonym(s):
N-[(2-bromo-5-?methoxyphenyl)methyl]-3-?pyridinamine, ZINC128734226
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About This Item
Empirical Formula (Hill Notation):
C13H13BrN2O
CAS Number:
Molecular Weight:
293.16
UNSPSC Code:
12352200
NACRES:
NA.77
Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
UCSF4226 (ZINC128734226) is brain permeable, potent and selective agonist of human melatonin hMT2 receptor.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Reed M Stein et al.
Nature, 579(7800), 609-614 (2020-02-11)
The neuromodulator melatonin synchronizes circadian rhythms and related physiological functions through the actions of two G-protein-coupled receptors: MT1 and MT2. Circadian release of melatonin at night from the pineal gland activates melatonin receptors in the suprachiasmatic nucleus of the hypothalamus
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