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Key Documents

S5758

Sigma-Aldrich

Sodium tetrathionate dihydrate

≥98% (titration)

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About This Item

Linear Formula:
NaO3SS2SO3Na · 2H2O
CAS Number:
Molecular Weight:
306.27
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.26

Quality Level

Assay

≥98% (titration)

solubility

H2O: 200 + 4mL H2O mg, clear to hazy, colorless to faintly yellow

density

2.1 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

O.O.[Na+].[Na+].[O-]S(=O)(=O)SSS([O-])(=O)=O

InChI

1S/2Na.H2O6S4.2H2O/c;;1-9(2,3)7-8-10(4,5)6;;/h;;(H,1,2,3)(H,4,5,6);2*1H2/q2*+1;;;/p-2

InChI key

HAEPBEMBOAIUPN-UHFFFAOYSA-L

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Application


  • Gaussia princeps luciferase: a bioluminescent substrate for oxidative protein folding.: Sodium tetrathionate dihydrate is used to study its impact on the oxidative folding of proteins, utilizing Gaussia princeps luciferase as a bioluminescent substrate. This study advances understanding of protein chemistry and bioluminescence applications in biochemical assays (Yu T et al., 2018).

  • https://doi.org/10.2174/092986612800190973
    https://doi.org/10.1080/10826068.2011.544230
    https://doi.org/10.11150/kansenshogakuzasshi.83.380
  • A spectroscopic investigation into the reaction of sodium tetrathionate with cysteine.: The research utilizes spectroscopic methods to study the reaction between sodium tetrathionate dihydrate and cysteine, providing insights into the chemical interactions and potential applications in biochemistry and molecular biology (Church JS et al., 2008).

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tadayoshi Kanao et al.
Journal of biotechnology, 132(1), 16-22 (2007-10-02)
Tetrathionate is one of the most important intermediates in dissimilatory sulfur oxidation and can itself be utilized as a sole energy source by some sulfur-oxidizing microorganisms. Tetrathionate hydrolase (4THase) plays a significant role in tetrathionate oxidation and should catalyze the
Daniel Kupka et al.
Research in microbiology, 160(10), 767-774 (2009-09-29)
Mesophilic iron and sulfur-oxidizing acidophiles are readily found in acid mine drainage sites and bioleaching operations, but relatively little is known about their activities at suboptimal temperatures and in cold environments. The purpose of this work was to characterize the
Carlos R Llerena-Suster et al.
Preparative biochemistry & biotechnology, 41(2), 107-121 (2011-03-29)
Papain from latex of Carica papaya was purified up to matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometry homogeneity by salt precipitation from two different crude extract sources: a refined preparation obtained in our laboratory and a commercial one. Sodium
Sebastian E Winter et al.
Nature, 467(7314), 426-429 (2010-09-25)
Salmonella enterica serotype Typhimurium (S. Typhimurium) causes acute gut inflammation by using its virulence factors to invade the intestinal epithelium and survive in mucosal macrophages. The inflammatory response enhances the transmission success of S. Typhimurium by promoting its outgrowth in
Sebastian E Winter et al.
Gut microbes, 2(1), 58-60 (2010-01-01)
Salmonella is a common cause of food poisoning. However, after ingestion the pathogen has to compete with resident microbes that already occupy the intestinal lumen (microbiota), which poses a challenge for Salmonella to successfully colonize this niche. Recent data show

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