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Key Documents

S3875

Sigma-Aldrich

Seleno-DL-methionine

≥99% (TLC)

Synonym(s):

2-amino-4-(methylseleno)-Butanoic acid

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About This Item

Empirical Formula (Hill Notation):
C5H11NO2Se
CAS Number:
Molecular Weight:
196.11
Beilstein:
1758204
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26

product name

Seleno-DL-methionine, ≥99% (TLC)

Quality Level

Assay

≥99% (TLC)

form

powder

color

white to off-white

application(s)

cell analysis

storage temp.

−20°C

SMILES string

C[Se]CCC(N)C(O)=O

InChI

1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)

InChI key

RJFAYQIBOAGBLC-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Susie Shih-Yin Huang et al.
Aquatic toxicology (Amsterdam, Netherlands), 126, 274-282 (2012-10-24)
Selenium (Se) and mercury (Hg) are prevalent pollutants of industrialized watersheds. However, when co-administered, Se has protective effects on organisms from Hg. The mechanism is not fully understood, but it is thought that Se reduces Hg availability, either by forming
Ian R Bothwell et al.
Journal of the American Chemical Society, 134(36), 14905-14912 (2012-08-25)
Posttranslational methylation by S-adenosyl-L-methionine(SAM)-dependent methyltransferases plays essential roles in modulating protein function in both normal and disease states. As such, there is a growing need to develop chemical reporters to examine the physiological and pathological roles of protein methyltransferases. Several
Vasundara Venkateswaran et al.
Cancer research, 62(9), 2540-2545 (2002-05-01)
Prostate cancer (PCA) is the most common histological malignancy and the second leading cause of cancer deaths among North American men. There has been considerable interest in the chemopreventative properties of selenium. In this study, we assessed whether selenium inhibits
Nikolay Solovyev et al.
Analytical and bioanalytical chemistry, 405(6), 1875-1884 (2012-08-08)
Se speciation was performed in 24 individual paired serum and cerebrospinal fluid (CSF) samples from neurologically healthy persons. Strong anion exchange (SAX) separation, coupled to inductively coupled plasma-dynamic reaction cell-mass spectrometry (ICP-DRC-MS), was employed. Species identification was done by standard
Stephanie A Schaefer et al.
Journal of molecular biology, 425(2), 222-231 (2012-11-20)
Sulfur, a key contributor to biological reactivity, is not amendable to investigations by biological NMR spectroscopy. To utilize selenium as a surrogate, we have developed a generally applicable (77)Se isotopic enrichment method for heterologous proteins expressed in Escherichia coli. We

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