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Key Documents

P6501

Sigma-Aldrich

Phenyl-β-D-galactopyranoside

≥98% (TLC)

Synonym(s):

P-Gal, Phenyl β-D-galactoside

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About This Item

Empirical Formula (Hill Notation):
C12H16O6
CAS Number:
Molecular Weight:
256.25
Beilstein:
87518
EC Number:
MDL number:
UNSPSC Code:
41141627
PubChem Substance ID:
NACRES:
NA.52

grade

for mineral oil production sites, untaxed

Quality Level

Assay

≥98% (TLC)

form

powder

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@@H](Oc2ccccc2)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H16O6/c13-6-8-9(14)10(15)11(16)12(18-8)17-7-4-2-1-3-5-7/h1-5,8-16H,6H2/t8-,9+,10+,11-,12-/m1/s1

InChI key

NEZJDVYDSZTRFS-YBXAARCKSA-N

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General description

Phenyl-β-D-galactopyranoside is used as a substrate for detecting β-galactosidase enzymatic activity.

Application

Phenyl-β-D-galactopyranoside has been used in mutant phage screening.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Zbynek Oktabec et al.
Molecules (Basel, Switzerland), 15(12), 8973-8987 (2010-12-15)
Mixtures of ibandronate monosodium salt with eleven gluco- and/or galacto-pyranoside derivatives as counterions were designed to prepare co-crystals with improved intestinal absorption. In general, gastrointestinal absorption of bisphosphonates after oral administration is approximately 1%. Co-crystals were generated by means of
M Ring et al.
Biochemical and biophysical research communications, 131(2), 675-680 (1985-09-16)
The pH profiles of beta-galactosidase, having tyr replaced by m-fluorotyrosine, were compared to those of normal enzyme. The inflection point on the alkaline side was lowered about 1.5 pH units in the fluoro-enzyme, corresponding to the difference in the phenolic
Ziyu Deng et al.
International journal of biological macromolecules, 137, 69-76 (2019-07-02)
β-Galactosidase (β-Gal) as dietary supplement has the ability to alleviate symptoms of lactose intolerance. This study investigated the ability of oligosaccharides to protect β-Gal against heat stress. Four kinds of oligosaccharides including Isomalto-oligosaccharides (IMO), Xylo-oligosaccharides (XOS), Konjac-oligosaccharides (KOS), and Mycose
Daniel D Mitchell et al.
Bioorganic & medicinal chemistry, 12(5), 907-920 (2004-02-26)
With the aim of developing high-affinity mono and multivalent antagonists of cholera toxin (CT) and Escherichia coli heat-labile enterotoxin (LT) we are using the galactose portion of the natural receptor ganglioside GM1 as an anchoring fragment in structure-based inhibitor design
E J Mientjes et al.
Mutation research, 360(2), 101-106 (1996-06-10)
The recent introduction of the phenyl-beta-D-galactopyranoside (P-gal)-based positive-selection system for screening of lambda lacZ phages originating from the lambda lacZ transgenic mouse (Muta Mouse) has made the determination of mutant frequencies (MF) a much simpler task. Previously, MF data from

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