P3440
Polyoxyethylene (40) stearate
Synonym(s):
Myrj 52
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About This Item
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description
non-ionic
Quality Level
form
powder
application(s)
detection
InChI
1S/C20H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)23-19-18-21/h21H,2-19H2,1H3
InChI key
RFVNOJDQRGSOEL-UHFFFAOYSA-N
General description
Polyoxyethylene (40) stearate is a neutral surfactant.
Application
Polyoxyethylene (40) stearate has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers. It has also been used in a study to investigate its effects on multidrug resistance (MDR).
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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The feasibility of a method based on mass preservation [G. Schwarz, J. Zhang, Chem. Phys. Lipids, 110 (2001) 35-45] to determine the solubility of Cholesterol in water from monomolecular films on air/water interface was investigated. Using a mass balance equation
Effects of polyoxyethylene (40) stearate on the activity of P-glycoprotein and cytochrome P450.
European Journal of Pharmaceutical Sciences, 37, 8-8 (2009)
The AAPS journal, 9(3), E329-E335 (2008-01-04)
Multidrug resistance (MDR) is one of the major obstacles limiting the efficacy of cancer chemotherapy. Identification of new and effective MDR reversal agents is needed. In this study, the effects of polyoxyethylene 40 stearate (PS40) on MDR were evaluated via
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International journal of pharmaceutics, 303(1-2), 54-61 (2005-08-18)
The purpose of the present study was to characterize the solid state properties of ternary solid dispersions made up of PVP VA64, Myrj 52 and itraconazole. The solid dispersions were prepared by dissolving the materials in methylene chloride, followed by
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