Skip to Content
Merck
All Photos(1)

Key Documents

M9917

Sigma-Aldrich

Mannan−Agarose

saline suspension

Synonym(s):

Mannan Binding Protein Agarose

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

MDL number:
MFCD00213010
UNSPSC Code:
23151817
NACRES:
NA.56

biological source

plant

Quality Level

200

form

saline suspension

technique(s)

affinity chromatography: suitable

matrix

cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

hydroxyl

matrix spacer

1 atom

capacity

≥30 mg/mL binding capacity (concanavalin A)

suitability

suitable for chromatography

storage temp.

2-8°C

Application

Mannan-agarose is used in protein chromatography, affinity chromatography and carbohydrate matrices. Mannan-agarose has been used in studies assessing poly(ADP-ribosyl)ation of mannose-binding lectin out of human kidney cells and to inform mannose-associated serine protease (MASP) activated components of the coagulation system. Mannan-agarose has also been used to study the innate immunity and resistance to Aeromonas salmonicida exhibited by the sea lamprey (Petromyzon marinus), a parasitic cartilaginous fish of the North American Great Lakes and a predator of many bony fish species of commercial importance to the fishing industry. Mannan-Agarose has been used to deplete rabbit anti-mannose-binding lectin (MBL) polyclonal antiserum of anti-mannan antibodies.

Physical form

Suspension in 1.0 M NaCl, 10 mM imidazole containing preservative

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Karlijn Gijzen et al.
Journal of leukocyte biology, 81(3), 729-740 (2006-12-01)
The role of dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN) in DC-T cell communication was assessed by analyzing the effect of DC-SIGN-blocking mAb in MLR. The results show that the degree of inhibition by DC-SIGN and LFA-1 mAb depends on the magnitude
Identification of Mannose-Binding Protein from Milkfish
(Chanos chanos F.) Serum
Argayosa AM, et al.
Biological Chemistry, 277- 288 (2015)
R J Raemaekers et al.
European journal of biochemistry, 265(1), 394-403 (1999-09-22)
Phytohemagglutinin (Phaseolus vulgaris agglutinin; PHA; E- and L-forms) and snowdrop lectin (Galanthus nivalis agglutinin; GNA) were expressed in Pichia pastoris using native signal peptides, or the Saccharomyces alpha-factor preprosequence, to direct proteins into the secretory pathway. PHA and GNA were
X Q Yu et al.
The Journal of biological chemistry, 275(48), 37373-37381 (2000-08-24)
A lipopolysaccharide-specific lectin, immulectin-2, was isolated from plasma of the tobacco hornworm, Manduca sexta. Immulectin-2 has specificity for xylose, glucose, lipopolysaccharide, and mannan. A cDNA clone encoding immulectin-2 was isolated from an Escherichia coli-induced M. sexta larval fat body cDNA
Donald D Ourth et al.
Fish & shellfish immunology, 23(6), 1152-1160 (2007-10-24)
Mannose-binding C-type lectin (MBL) was isolated from channel catfish (Ictalurus punctatus) NWAC 102 and 103 strains, blue catfish (Ictalurus furcatus) D+B and Rio Grande strains, hybrid catfish (channel catfish female NWAC 103 x blue catfish male D+B) sera, and purified
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service