C0735

8-(4-Chlorophenylthio)adenosine-3′,5′-cyclic Monophosphorothioate, Rp-isomer sodium salt

≥99% (HPLC), solid

• Synonym(s): Rp-8-CPT-cAMPS
• Empirical Formula (Hill Notation): C₁₆H₁₄ClN₅O₅PS₂Na
• CAS Number: 129735-01-9
• Molecular Weight: 509.86
• MDL number: MFCD04113743
• UNSPSC Code: 41106305
• PubChem Substance ID: 24892271
• NACRES: NA.77

Properties

• biological source: synthetic (organic)
• Quality Level: 200
• Assay: ≥99% (HPLC)
• form: solid
• packaging: vial of 5 μmol
• storage temp.: −20°C
• SMILES string: [Na+].Nc1ncnc2n([C@@H]3O[C@@H]4COP([S-])(=O)O[C@H]4[C@H]3O)c(Sc5ccc(Cl)cc5)nc12
• InChI: 1S/C16H15ClN5O5PS2.Na/c17-7-1-3-8(4-2-7)30-16-21-10-13(18)19-6-20-14(10)22(16)15-11(23)12-9(26-15)5-25-28(24,29)27-12;/h1-4,6,9,11-12,15,23H,5H2,(H,24,29)(H2,18,19,20);/q;+1/p-1/t9-,11-,12-,15-,28?;/m1./s1
• InChI key: AWXMSJRRXLCVMW-JVSRKQJHSA-M

Description

Biochem/physiol Actions

Lipophilic analog of the competitive inhibitor of protein kinase A (cyclic AMP antagonist).

Features and Benefits

This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves