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A9754

Sigma-Aldrich

2-Amino-2-methyl-1,3-propanediol

≥99%

Synonym(s):

AMPD, Ammediol

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About This Item

Linear Formula:
(HOCH2)2C(NH2)CH3
CAS Number:
115-69-5
Molecular Weight:
105.14
Beilstein:
635708
EC Number:
204-100-7
MDL number:
MFCD00004678
UNSPSC Code:
12161700
PubChem Substance ID:
24891493
NACRES:
NA.25

vapor density

3.63 (vs air)

Quality Level

300

vapor pressure

~10 mmHg ( 152 °C)

Assay

≥99%

form

crystalline

pH

10.5-11.5 (25 °C, 105.1 g/L)

useful pH range

7.8-9.7

pKa (25 °C)

8.8

bp

151 °C/10 mmHg (lit.)

mp

100-110 °C (lit.)

solubility

H2O: 100 mg/mL, clear to slightly hazy, colorless to very faintly yellow

application(s)

diagnostic assay manufacturing

SMILES string

CC(N)(CO)CO

InChI

1S/C4H11NO2/c1-4(5,2-6)3-7/h6-7H,2-3,5H2,1H3

InChI key

UXFQFBNBSPQBJW-UHFFFAOYSA-N

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Related Categories

Application

Buffer component in a SDS-gradient gel electrophoresis system that separates polypeptides in the molecular weight range of 1500 to 100,000. Used as a spacer in isotachophoresis of proteins. Also used as a buffer for the determination of alkaline phosphatase activity.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

>212.0 °F

Flash Point(C)

> 100 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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2-Amino-2-methyl-1-propanol BioXtra, ≥95%

Sigma-Aldrich

A9199

2-Amino-2-methyl-1-propanol

3-Amino-1,2-propanediol for synthesis

Sigma-Aldrich

8.18522

3-Amino-1,2-propanediol

Masahiro Fukuyama et al.
Frontiers in cell and developmental biology, 9, 590333-590333 (2021-08-20)
Current approaches for human hair follicle (HF) regeneration mostly adopt cell-autonomous tissue reassembly in a permissive murine intracorporeal environment. This, together with the limitation in human-derived trichogenic starting materials, potentially hinders the bioengineering of human HF structures, especially for the
Murugappan Sathappa et al.
Bio-protocol, 6(22) (2016-12-09)
Biological membranes are vital for diverse cellular functions such as maintaining cell and organelle structure, selective permeability, active transport, and signaling. The surface charge of the membrane bilayer plays a critical role in these myriad processes. For most biomembranes, the
Takayuki Yakura et al.
Chemical & pharmaceutical bulletin, 55(9), 1385-1389 (2007-09-11)
Dirhodium(II)-catalyzed C-H amination reaction of (S)-3-(tert-butyldimethylsilyloxy)-2-methylpropyl carbamate, which was easily prepared from methyl (S)-2-methyl-3-hydroxypropanoate, proceeded more smoothly than those of their 2-(methoxycarbonyl)propyl derivative to give the corresponding oxazolidinone in excellent yield. The resulting oxazolidinone was converted efficiently into both (R)-monoprotected
H Kikuchi et al.
The Tohoku journal of experimental medicine, 173(4), 391-397 (1994-08-01)
The method by MacQueen and Plaut was modified to devise simple microdetermination method of l-lactate which is applicable to deproteinized blood sample. Blood was deproteinized with addition of 25% (w/w) trichloroacetic acid (TCA), and 0.075 M 2-amino-2-methyl-1, 3-propanediole (AMPD) was
Karen M O'Connor et al.
Journal of pharmaceutical sciences, 91(10), 2271-2281 (2002-09-13)
Dissolution of diclofenac from compressed discs containing mixtures of a diclofenac salt and a basic excipient, in various w/w ratios, was examined. Two diclofenac salts, diclofenac deanol (DDNL) and diclofenac tert-butylamine, and the basic excipient 2-amino-2-methyl-1,3-propanediol (AMPD) were examined. Inclusion
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