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Key Documents

A3133

Sigma-Aldrich

Nα-Acetyl-L-arginine

≥98% (TLC), suitable for deacetylase assays

Synonym(s):

N2-acetyl-L-alanine

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About This Item

Empirical Formula (Hill Notation):
C8H16N4O3
CAS Number:
Molecular Weight:
216.24
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

product name

Nα-Acetyl-L-arginine,

Assay

≥98% (TLC)

Quality Level

form

powder

technique(s)

deacetylase assay: suitable

color

colorless to white

storage temp.

−20°C

SMILES string

NC(NCCC[C@H](NC(C)=O)C(O)=O)=N

InChI

1S/C8H16N4O3/c1-5(13)12-6(7(14)15)3-2-4-11-8(9)10/h6H,2-4H2,1H3,(H,12,13)(H,14,15)(H4,9,10,11)/t6-/m0/s1

InChI key

SNEIUMQYRCDYCH-LURJTMIESA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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T W Lo et al.
The Journal of biological chemistry, 269(51), 32299-32305 (1994-12-23)
The physiological alpha-oxoaldehyde methylglyoxal binds and modifies arginine, lysine, and cysteine residues in proteins. The kinetics and mechanism of these reactions were investigated with N alpha-acetylamino acids and bovine serum albumin at pH 7.4 and 37 degrees C. The reaction
Z Zhang et al.
Nature structural biology, 7(2), 127-133 (2000-02-03)
Clavaminate synthase (CAS), a remarkable Fe(II)/2-oxoglutarate oxygenase, catalyzes three separate oxidative reactions in the biosynthesis of clavulanic acid, a clinically used inhibitor of serine beta-lactamases. The first CAS-catalyzed step (hydroxylation) is separated from the latter two (oxidative cyclization/desaturation) by the
P De Deyn et al.
Clinica chimica acta; international journal of clinical chemistry, 157(2), 143-150 (1986-06-15)
The concentrations of guanidino compounds in blood are raised in uraemic patients and may have toxic effects. The concentrations of 13 guanidino compounds in serum were measured in 29 patients with chronic renal failure treated by chronic intermittent haemodialysis using
P P De Deyn et al.
Nephron, 69(4), 411-417 (1995-01-01)
Serum levels of twelve guanidino compounds (GCs) and nerve conduction velocities were determined in a dialyzed renal insufficient pediatric population. Two dialytic groups were considered: one subjected to hemodialysis (HD, 11 patients) and one subjected to continuous cycle peritoneal dialysis
Joshua L Deignan et al.
Molecular genetics and metabolism, 100 Suppl 1, S31-S36 (2010-02-24)
The paucity of hyperammonemic crises together with spasticity, only seen in human arginase I deficient patients and not in patients with other urea cycle disorders, forces a search for candidates other than ammonia to associate with the pathophysiology and symptomatology.

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