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Key Documents

96329

Sigma-Aldrich

Kollicoat® SR 30 D

28.5-31.5% solids basis

Synonym(s):

Poly(vinyl acetate) dispersion 30 %, Poly(vinyl acetate) stabilized with polyvinylpyrrolidone and sodium lauryl sulfate

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About This Item

CAS Number:
9003-20-7
MDL number:
MFCD00084457
UNSPSC Code:
12162002
NACRES:
NA.25

Quality Level

100

Assay

25.0-30.0% (saponification value * 0.1534)
28.5-31.5% solids basis

form

dispersion

impurities

≤0.5% sulfated ash (verified on random samples only)
≤0.500% particulate matter, agglomerates
≤100 ppm residual monomer vinyl acetate
≤15000 ppm acetic acid
≤20 ppm heavy metals (verified on random samples only)
≤4.0% povidone (N content/0.126)

pH

3.0-5.5

viscosity

≤100 mPa.s(20 °C, Brookfield RVT) (SP. 1, 100 PRM)

density

1.045-1.065

InChI

1S/C4H6O2/c1-3-6-4(2)5/h3H,1H2,2H3

InChI key

XTXRWKRVRITETP-UHFFFAOYSA-N

Application

Kollicoat SR is use as a controlled-release coating or as a matrix. Kollicoat polymers can be employed as film coatings (intelligent surfaces) with controlled-release agents, for instant-release or sustained-release applications. Kollicoat polymers can be used with all standard coating equipment and are cost-effective, delivering maximum quality in terms of function, stability, and appearance. This research grade product is intended for use in R&D and development only.

Analysis Note

appearance and solubility of a film must conform

Legal Information

Kollicoat is a registered trademark of BASF SE

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Wiesław Sawicki et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 60(1), 153-158 (2005-04-26)
The purpose of this study was to work out a method of compression of floating pellets with verapamil hydrochloride (VH) in a dose of 40 mg. It was assumed that this form should reside in the stomach floating for several
Nizar Al-Zoubi et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 735-742 (2008-02-23)
Sustained-release of buspirone HCl (BUH) was attempted by spray drying after dissolving in two commercially available aqueous polymeric dispersions (Eudragit RS 30 D or Kollicoat SR 30 D) at five different drug:polymer ratios (1:1, 1:2, 1:3, 1:6 and 1:9). The
Sandra Strübing et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 708-717 (2008-02-06)
The purpose of this study was to investigate the mechanism of floating and drug release behaviour of poly(vinyl acetate)-based floating tablets with membrane controlled drug delivery. Propranolol HCl containing tablets with Kollidon SR as an excipient for direct compression and
Seon Tae Kim et al.
International journal of pediatric otorhinolaryngology, 77(1), 113-116 (2012-11-08)
The purpose of this prospective study was to determine the effectiveness of polyurethane foam (PUF) and polyvinyl acetate (PA) as packing materials for reducing post-conchotomy bleeding, pain, and headaches. This study was a prospective, randomized and single-blinded controlled study. Fifty-two
Priscileila Colerato Ferrari et al.
Carbohydrate polymers, 91(1), 244-252 (2012-10-10)
In this work pellets containing chitosan for colonic drug delivery were developed. The influence of the polysaccharide in the pellets was evaluated by swelling, drug dissolution and intestinal permeation studies. Drug-loaded pellets containing chitosan as swellable polymer were coated with
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