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40232

Sigma-Aldrich

N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate

≥97.0% (dried material, CHN)

Synonym(s):

3-(N,N-Dimethyldodecylammonio)propanesulfonate, 3-(N,N-Dimethyllaurylammonio)propanesulfonate, 3-(Dodecyldimethylammonio)propanesulfonate, 3-(Lauryldimethylammonio)propanesulfonate, Dodecyldimethyl(3-sulfopropyl)ammonium hydroxide inner salt, Lauryl sulfobetaine, SB3-12

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About This Item

Linear Formula:
CH3(CH2)11N+(CH3)2CH2CH2CH2SO3-
CAS Number:
14933-08-5
Molecular Weight:
335.55
Beilstein:
4145308
EC Number:
239-002-3
MDL number:
MFCD00036909
UNSPSC Code:
12161900
eCl@ss:
32190102
PubChem Substance ID:
57649944
NACRES:
NA.25

description

zwitterionic

Quality Level

200

Assay

≥97.0% (dried material, CHN)

form

powder

mol wt

micellar avg mol wt 18,500

aggregation number

55

ign. residue

≤0.1%

loss

≤1% loss on drying, 110 °C

CMC

2-4 mM (20-25°C)

cation traces

Ca: ≤20 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤150 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

application(s)

detection

SMILES string

CCCCCCCCCCCC[N+](C)(C)CCCS([O-])(=O)=O

InChI

1S/C17H37NO3S/c1-4-5-6-7-8-9-10-11-12-13-15-18(2,3)16-14-17-22(19,20)21/h4-17H2,1-3H3

InChI key

IZWSFJTYBVKZNK-UHFFFAOYSA-N

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General description

N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate is a zwitterionic detergent that is used for protein solubilization.

Application

N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate has been used as a component of trypsin buffer for the dialysis of protein solution.

Other Notes

Zwitterionic surfactant which effectively solubilizes cardiac 5′-nucleotidase

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

110 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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D Boehning et al.
The EMBO journal, 19(20), 5450-5459 (2000-10-18)
Inositol 1,4,5-trisphosphate receptors (IP(3)Rs) are a family of intracellular Ca(2+) channels that exist as homo- or heterotetramers. In order to determine whether the N-terminal ligand-binding domain is in close physical proximity to the C-terminal pore domain, we prepared microsomal membranes
María Muñoz et al.
Langmuir : the ACS journal of surfaces and colloids, 20(25), 10858-10867 (2004-12-01)
Micellization in sodium dodecyl sulfate (SDS)-N-dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate and SDS-polyoxyethylenesorbitan monolaurate binary surfactant solutions was studied by means of conductivity and surface tension measurements. These studies showed that two types of micellar aggregates are present in the mixed micellar solutions. Two reactions
H L Liou et al.
Biochemistry, 40(21), 6475-6485 (2001-05-24)
The tertiary structure of murine adipocyte fatty acid-binding protein (AFABP) is a flattened 10-stranded beta-barrel capped by a helix-turn-helix segment. This helical domain is hypothesized to behave as a "lid" or portal for ligand entry into and exit from the
Marien I de Jonge et al.
European journal of biochemistry, 269(21), 5215-5223 (2002-10-24)
Opacity-associated (Opa) proteins are outer membrane proteins which play a critical role in the adhesion of pathogenic Neisseria spp. to epithelial and endothelial cells and polymorphonuclear neutrophils. The adherence is mainly mediated by the CD66-epitope-containing members of the carcinoembryonic-antigen family
W Hu et al.
The Analyst, 125(3), 447-451 (2000-06-01)
A new ion chromatographic (IC) system, which uses zwitterionic (e.g., Zwittergent 3-14) micelles as both stationary and mobile phases, highly useful for the analysis of inorganic anions in biological samples, was developed. The zwitterionic micellar stationary phase (which is obtained
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