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Merck

P8574

Sigma-Aldrich

Sodium pyruvate

BioXtra, ≥99%

Synonym(s):

α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt, Pyruvic acid sodium salt

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About This Item

Linear Formula:
CH3COCOONa
CAS Number:
Molecular Weight:
110.04
Beilstein:
3568341
EC Number:
MDL number:
UNSPSC Code:
12352207
PubChem Substance ID:
NACRES:
NA.71

Pricing and availability is not currently available.

product line

BioXtra

Quality Level

Assay

≥99%

form

powder

impurities

≤0.005% Phosphorus (P)
≤0.1% Insoluble matter

mp

>300 °C (lit.)

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.001%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

storage temp.

2-8°C

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Application

Sodium pyruvate has been used as a component:
  • of cutting solution for rat brain tissue slice preparation[1]
  • of M-199 medium for the maturation of oocytes[2]
  • of Krebs-Henseleit buffer for plasma incubation[3]

Biochem/physiol Actions

Sodium pyruvate based therapeutic regimen is effective for treating mitochondrial diseases.[4] It decreases tissue damage associated with the pathophysiology of brain damage, haemorrhagic shock and ischemia-reperfusion injury models.[5]

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1B

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Biomarkers and clinical rating scales for sodium pyruvate therapy in patients with mitochondrial disease
Koga Y, et al.
Mitochondrion (2019)
Transcriptome and proteome analysis of soleus muscle of hormone-sensitive lipase-null mice
Hansson O, et al.
Journal of Lipid Research, 46(12), 2614-2623 (2005)
Imaging calcium concentration dynamics in small neuronal compartments
Yasuda R, et al.
Science's STKE : Signal Transduction Knowledge Environment, 2004(219) (2004)
Addition of sodium pyruvate to stored red blood cells attenuates liver injury in a murine transfusion model
Xia S, et al.
Mediators of Inflammation, 2016 (2016)
Embryonic development after follicle culture is influenced by follicle-stimulating hormone isoelectric point range
Vitt UA, et al.
Biology of Reproduction, 65(5) (2001)

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