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Key Documents

P6148

Sigma-Aldrich

Paraformaldehyde

reagent grade, crystalline

Synonym(s):

Polyoxymethylene

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About This Item

Linear Formula:
HO(CH2O)nH
CAS Number:
Molecular Weight:
30.03 (as monomer)
MDL number:
UNSPSC Code:
12352114
PubChem Substance ID:
NACRES:
NA.25

grade

reagent grade

Quality Level

vapor density

1.03 (vs air)

vapor pressure

<1.45 mmHg ( 25 °C)

form

crystalline

autoignition temp.

572 °F

expl. lim.

73 %

mp

120-170 °C (lit.)

density

0.88 g/mL at 25 °C (lit.)

storage temp.

2-8°C

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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General description

Paraformaldehyde is a cross-linking fixative. It is changed to formaldehyde by heating and by adding small amount of sodium hydroxide.

Application

Paraformaldehyde is recommended for use in the preparation of formalin fixatives for tissues or cells when the samples are to be used in florescence studies.
Paraformaldehyde has been used for fixing of cells and tissue sections during staining procedures.

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Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Flam. Sol. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

4.1B - Flammable solid hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Molecular Plant Biology: A Practical Approach (2002)
The development of 3-D, in vitro, endothelial culture models for the study of coronary artery disease.
Farcas MA et al.
BioMedical Engineering OnLine, 8, 30-30 (2009)
Proliferation of bone marrow-derived cells contributes to regeneration after folic acid-induced acute tubular injury.
Fang TC, et al.
Journal of the American Society of Nephrology, 16, 1723-1723 (2005)
Burry RW
Immunocytochemistry: A Practical Guide for Biomedical Research (2009)
Ying Wang et al.
PloS one, 12(7), e0180731-e0180731 (2017-07-08)
Mutations in the immunoglobulin superfamily, member 1 gene (IGSF1/Igsf1) cause an X-linked form of central hypothyroidism. The canonical form of IGSF1 is a transmembrane glycoprotein with 12 immunoglobulin (Ig) loops. The protein is co-translationally cleaved into two sub-domains. The carboxyl-terminal

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Protocols

Cell staining can be divided into four steps: cell preparation, fixation, application of antibody, and evaluation.

Cell staining can be divided into four steps: cell preparation, fixation, application of antibody, and evaluation.

Cell staining can be divided into four steps: cell preparation, fixation, application of antibody, and evaluation.

Cell staining can be divided into four steps: cell preparation, fixation, application of antibody, and evaluation.

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