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Key Documents

L0800000

Lynestrenol

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

(17α)-19-Norpregn-4-en-20-yn-17-ol

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About This Item

Empirical Formula (Hill Notation):
C20H28O
CAS Number:
52-76-6
Molecular Weight:
284.44
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

lynestrenol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C20H28O/c1-3-20(21)13-11-18-17-9-8-14-6-4-5-7-15(14)16(17)10-12-19(18,20)2/h1,6,15-18,21H,4-5,7-13H2,2H3/t15-,16+,17+,18-,19-,20-/m0/s1

InChI key

YNVGQYHLRCDXFQ-XGXHKTLJSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lynestrenol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Yasir Hasan Siddique et al.
Indian journal of experimental biology, 43(3), 291-293 (2005-04-09)
Genotoxicity study of synthetic progestin lynestrenol, was carried out on mouse bone marrow cells using sister chromatid exchanges (SCEs) and chromosomal aberrations (CAs) as parameters. Lynestrenol was studied at three different doses (6.87, 13.75 and 27.50 mg/kg body wt.). SCE
Ozlem Ozdegirmenci et al.
Gynecologic and obstetric investigation, 72(1), 10-14 (2011-01-27)
To evaluate the treatment of endometrial hyperplasia (EH) with different progestins. Eighty-two women with simple EH without atypia were included. Patients were offered oral progestagens and were randomized to one of three options for 3 months: medroxyprogesterone acetate (MPA, 10
Eva-Katrin Bentz et al.
Fertility and sterility, 94(7), 2688-2696 (2010-06-12)
To evaluate gene expression signatures of breast tissue in female-to-male (FtM) transsexuals under cross-sex hormone therapy (HT). Prospective cohort study. Academic research institution. Five hormone-naïve FtM transsexuals before and after HT. Breast tissue biopsy before and after 2 years of
M Jangidze et al.
Georgian medical news, (141)(141), 21-26 (2007-01-31)
The aim of the study was the investigation of impact of different hormonal contraceptive drugs on cervix of uterus of young nullipara women with ectopia. Cytologic smears were examined using Pappanikolau method. Cohort study was carried out by using simple
Sanna Palovaara et al.
British journal of clinical pharmacology, 56(2), 232-237 (2003-08-05)
To study the effect of an oral contraceptive (OC) formulation containing ethinyloestradiol and levonorgestrel (LNG) (combination OC) or LNG alone on the CYP2C19-mediated hydroxylation of omeprazole in healthy females. This was an open crossover study with three phases. In phase
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