ED2P

Ethylenediaminetetraacetic acid dipotassium salt dihydrate

≥98%

• Synonym(s): (Ethylenedinitrilo)tetraacetic acid dipotassium salt, Dipotassium ethylenediaminetetraacetate dihydrate, EDTA dipotassium salt, Edathamil, Potassium ethylenediaminetetraacetate dibasic
• Linear Formula: HOOCCH₂(KOOCCH₂)NCH₂CH₂N(CH₂COOK)CH₂COOH · 2H₂O
• CAS Number: 25102-12-9
• Molecular Weight: 404.45
• EC Number: 217-895-0
• UNSPSC Code: 12352107
• NACRES: NA.77

Properties

• biological source: synthetic
• Quality Level: 200
• Assay: ≥98%
• form: powder
• reaction suitability: reagent type: chelator
• pH: 4.0-5.0 (25 °C, 40.4 g/L)
• mp: 255-280 °C (dec.) (lit.)
• solubility: 3 M KOH: 160 mg/mL, clear to very slightly hazy, colorless to faintly yellow
• storage temp.: room temp
• SMILES string: O.O.O.O.[K+].[K+].[K+].[K+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
• InChI: 1S/C10H16N2O8.2K.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
• InChI key: JFROQFOCFOKDKU-UHFFFAOYSA-L

Description

Application

Ethylenediaminetetraacetic acid dipotassium salt dehydrate has been used as a component:

• of EDTA–glycerol solution (EDTA-G) for decalcification
• of buffer for monoamine and pterine analysis
• of T-cell resuspension buffer

Used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals

Biochem/physiol Actions

Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood. EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia. EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis. Calcium disodium EDTA administration is effective in slowing down the progression of chronic kidney disease. It also enhances the antimicrobial functionality of lysozyme and improves shelf life of cheese.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H332
• Precautionary Statements: P261 - P271 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Inhalation
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves