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Key Documents

C2285000

Clobetasone butyrate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

21-Chloro-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione 17-butyrate

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About This Item

Empirical Formula (Hill Notation):
C26H32ClFO5
CAS Number:
Molecular Weight:
478.98
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

clobetasone

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CCCC(=O)O[C@@]1([C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)C(=O)C[C@]12C)C(=O)CCl

InChI

1S/C26H32ClFO5/c1-5-6-22(32)33-26(21(31)14-27)15(2)11-19-18-8-7-16-12-17(29)9-10-23(16,3)25(18,28)20(30)13-24(19,26)4/h9-10,12,15,18-19H,5-8,11,13-14H2,1-4H3/t15-,18-,19-,23-,24-,25-,26-/m0/s1

InChI key

FBRAWBYQGRLCEK-AVVSTMBFSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Clobetasone butyrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Ilknur Bostanci et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 15(3), 267-269 (2004-06-24)
Leptin, the obese gene product, is a 16-kDa peptide hormone secreted by adiposities. Systemic administration of exogenous glucocorticoids has been found to increase circulating leptin levels. In this study, we aimed to assess serum leptin in children with atopic dermatitis
Acute anterior uveitis.
André Curi et al.
Clinical evidence, (10)(10), 721-726 (2004-11-24)
Concomitant sensitivity to sodium metabisulfite and clobetasone butyrate in Trimovate cream.
D A Harrison et al.
Contact dermatitis, 46(5), 310-310 (2002-06-27)
Joanna Wallengren
Archives of dermatological research, 303(5), 333-338 (2010-09-25)
Herbs and minerals have been used in clinical dermatology for hundreds of years and herbal ingredients are becoming increasingly popular with the public in treatment of various dermatological conditions characterised by inflammation and pruritus. The aim of this study was
Equal efficacy of topical tacrolimus and clobetasone butyrate in pemphigus foliaceus.
Stuart N Cohen et al.
International journal of dermatology, 45(11), 1379-1379 (2006-11-02)

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