940356

GPhos Pd G3 ChemBeads

• Synonym(s): Methanesulfonato[Dicyclohexyl[3-(1,1-dimethylethoxy)-6-methoxy-2′,6′-bis(1-methylethyl)[1,1′-biphenyl]-2-yl]phosphine](2′-amino-1,1′-biphenyl-2-yl)palladium(II) ChemBeads
• Empirical Formula (Hill Notation): C₄₈H₆₆NO₅PPdS
• CAS Number: 2489525-82-6
• Molecular Weight: 906.50
• UNSPSC Code: 12352100

Properties

• form: solid
• Quality Level: 100
• composition: , 4-6 wt. % (loading)
• reaction suitability: reagent type: catalyst
• SMILES string: O=S(O[Pd]([P](C1CCCCC1)(C2CCCCC2)C3=C(C4=C(C(C)C)C=CC=C4C(C)C)C(OC)=CC=C3OC(C)(C)C)C5=C(C6=C(N)C=CC=C6)C=CC=C5)(C)=O
• InChI: InChI=1S/C35H53O2P.C12H10N.CH4O3S.Pd/c1-24(2)28-20-15-21-29(25(3)4)32(28)33-30(36-8)22-23-31(37-35(5,6)7)34(33)38(26-16-11-9-12-17-26)27-18-13-10-14-19-27;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-5(2,3)4;/h15,20-27H,9-14,16-19H2,1-8H3;1-6,8-9H,13H2;1H3,(H,2,3,4);/q;;;+1/p-1
• InChI key: PLMOFCQYSAAMKA-UHFFFAOYSA-M

Description

General description

The ChemBeads product of the GPhos ligand combined with the Buchwald third Generation Palladacycle. The GPhos motif gives superb activity while having greater stability relative to other superbulky Buchwald ligands. Loaded at 5% wt. on glass beads for use in high-throughput expermentation (HTE). GPhos Pd G3 has been used in: - The production of chiral N-arylamines via a telescoped transaminase-Buchwald-Hartwig Amination cascade.

Application

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical. For general uses, product is also available in powdered form (920460 )

Features and Benefits

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3