90268
Polyvinylpyrrolidone
K 25, tested according to Ph. Eur.
Synonym(s):
PVP, Polyvidone, Povidone
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About This Item
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Agency
tested according to Ph. Eur.
Quality Level
form
powder
SMILES string
C=CN1CCCC1=O
InChI
1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2
InChI key
WHNWPMSKXPGLAX-UHFFFAOYSA-N
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Application
- Colyophilized Sugar-Polymer Dispersions for Enhanced Processing and Storage Stability.: This study explores the use of polyvinylpyrrolidone in colyophilized sugar-polymer dispersions to improve the processing and storage stability of pharmaceuticals. The research demonstrates how combining sugars with polyvinylpyrrolidone enhances the physical stability and performance of the resulting dispersions, which is crucial for maintaining drug efficacy during storage and handling (Giannachi et al., 2024).
- Fabrication and evaluation of stable amorphous polymer-drug composite particles via a nozzle-free ultrasonic nebulizer.: This article discusses the development of amorphous polymer-drug composite particles using polyvinylpyrrolidone and a nozzle-free ultrasonic nebulizer. The findings indicate that polyvinylpyrrolidone helps in stabilizing the amorphous form of the drug, which can enhance its solubility and bioavailability (Lee et al., 2024).
- Polymer-Assisted Coprecipitation Synthesized Zinc Oxide Nanoparticles and Their Uses for Gre en Chemical Synthesis via Photocatalytic Glucose Conversions.: This study presents a novel method of using polyvinylpyrrolidone in the synthesis of zinc oxide nanoparticles. The research shows that these nanoparticles can be used in green chemical processes, such as the photocatalytic conversion of glucose, showcasing the versatility of polyvinylpyrrolidone in catalysis and material science (Kaewsaenee et al., 2023).
- Development and evaluation of the in vitro schistosomicidal activity of solid dispersions based on 2-(-5-bromo-1-H-indole-3-yl-methylene)-N-(naphthalene-1-ylhydrazine-carbothiamide).: This article explores the use of polyvinylpyrrolidone in formulating solid dispersions for antiparasitic treatments. The findings demonstrate that polyvinylpyrrolidone can enhance the solubility and efficacy of the active pharmaceutical ingredient against parasitic infections (de Luna Rocha et al., 2024).
Other Notes
Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Jennifer Quirós et al.
Journal of hazardous materials, 299, 298-305 (2015-07-05)
The use of electrospun polyvinylpyrrolidone (PVP) nanofibers containing silver, copper, and zinc nanoparticles was studied to prepare antimicrobial mats using silver and copper nitrates and zinc acetate as precursors. Silver became reduced during electrospinning and formed nanoparticles of several tens
Na0.44 MnO2 with very fast sodium diffusion and stable cycling synthesized via polyvinylpyrrolidone-combustion method.
Dai K, et al.
Journal of Power Sources, 285, 161-168 (2015)
Kallum M Koczkur et al.
Dalton transactions (Cambridge, England : 2003), 44(41), 17883-17905 (2015-10-06)
Colloidal synthesis offers a route to nanoparticles (NPs) with controlled composition and structural features. This Perspective describes the use of polyvinylpyrrolidone (PVP) to obtain such nanostructures. PVP can serve as a surface stabilizer, growth modifier, nanoparticle dispersant, and reducing agent.
Markéta Julinová et al.
Water environment research : a research publication of the Water Environment Federation, 84(12), 2123-2132 (2013-01-25)
Polyvinylpyrrolidone (PVP) is a frequently used polymer in the pharmaceutical and foodstuff industries. Because it is not subject to metabolic changes and is virtually nondegradable, trace concentrations of PVP are often found in community wastewaters. The literature finds that the
Sung Neung Lee et al.
Archives of pharmacal research, 36(1), 79-85 (2013-01-19)
A novel surface-attached, spray-dried solid dispersion containing poorly water-soluble carvedilol (CV) without any change in the crystallinity was prepared using water, polyvinylpyrrolidone (PVP K30) and Tween 80. The solid dispersion was optimized by investigating the effects of the weight ratios
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