84230
Salicylamide
puriss., ≥99.0% (T)
Synonym(s):
2-Hydroxybenzamide
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About This Item
Linear Formula:
2-(HO)C6H4CONH2
CAS Number:
Molecular Weight:
137.14
Beilstein:
742439
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
grade
puriss.
Quality Level
Assay
≥99.0% (T)
form
solid
mp
139-141 °C
140-144 °C (lit.)
solubility
methanol: 0.1 g/mL, clear
functional group
amide
SMILES string
NC(=O)c1ccccc1O
InChI
1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
InChI key
SKZKKFZAGNVIMN-UHFFFAOYSA-N
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Related Categories
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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R Dolezal et al.
European journal of medicinal chemistry, 44(2), 869-876 (2008-06-13)
Quantitative relationships between the molecular structure and the biological activity of 49 isosteric salicylamide derivatives as potential antituberculotics with a new mechanism of action against three Mycobacterial strains were investigated. The molecular structures were represented by quantum chemical B3LYP/6-31G( *)
S Zhang et al.
Transplantation proceedings, 38(5), 1247-1252 (2006-06-27)
Cardiac ischemia/reperfusion (I/R) injury, a necessary consequence of transplantation, is probably related to the formation of reactive oxygen species (ROS). The ROS burst within the first moments of reperfusion is associated with injury, continuously generate O2- at about 3% to
Stephanie S Barnes et al.
Dalton transactions (Cambridge, England : 2003), 40(17), 4707-4714 (2011-03-25)
Addition of boranes to N-aryl-salicylaldimines takes place initially at the reactive phenolic O-H bond to give an activated boron-containing imine and dihydrogen. In some cases a subsequent intramolecular hydrogenation step is observed and the C=N imine bond is reduced to
J A Murillo Pulgarín et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 909-914 (2011-05-13)
A new methodology for the simultaneous determination of salicylic acid and salicylamide in biological fluids is proposed. The strong overlapping of the fluorescence spectra of both analytes makes impossible the conventional fluorimetric determination. For that reason, the use of fluorescence
Silvia Wein et al.
Xenobiotica; the fate of foreign compounds in biological systems, 42(5), 477-482 (2011-12-23)
We investigated acute effects and effects after chronic intake of the orally administered flavonol quercetin on pharmacokinetics of salicylamide metabolites (SAM) after oral administration of salicylamide in pigs. Salicylamide (8 mg/kg body weight) was orally administered to seven pigs either
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