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Supelco

Ammelide

analytical standard

Synonym(s):

2-Amino-1,3,5-triazine-4,6-dione

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About This Item

Empirical Formula (Hill Notation):
C3H4N4O2
CAS Number:
Molecular Weight:
128.09
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥98.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

SMILES string

Nc1nc(O)nc(O)n1

InChI

1S/C3H4N4O2/c4-1-5-2(8)7-3(9)6-1/h(H4,4,5,6,7,8,9)

InChI key

YSKUZVBSHIWEFK-UHFFFAOYSA-N

General description

Ammelide (AMD), a 1,3,5-triazine compound, is one of the hydrolysis by-products of melamine. It is most commonly found as an impurity in melamine and its structural analog, cyanuric acid feedstocks.
Ammelide can be synthesized via hydrolysis of 2-amino-4,6-dichloro-s-triazine in the presence of acid or base or by the reaction between urea and cyanogen iodide at 130-140 degrees.

Application

Ammelide may be used as an analytical reference standard for the determination of the analyte in milk, milk products and infant formula using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Rapoport, L. and Smolin, ME
The Chemistry of Heterocyclic Compounds, 26 (2009)
Mechanistic and spectral investigation on the deamination of ammeline and ammelide
Almatarneh HM, et al.
Computational & Theoretical Chemistry, 1117, 92-99 (2017)
Rapid screening and quantification of cyromazine, melamine, ammelide, ammeline, cyanuric acid, and dicyandiamide in infant formula by ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry and triple quadrupole mass spectrometry
Meng Z, et al.
Food Control, 55(2), 158-165 (2015)
Limin He et al.
Journal of separation science, 32(19), 3310-3318 (2009-09-02)
A method for molecularly imprinted SPE of the melamine from environmental water samples was investigated. Cyromazine-imprinted polymers were synthesized in water-methanol systems for the selective extraction of melamine from aqueous samples, followed by HPLC analysis. Molecular recognition properties and binding
Paul M Murphy et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(23), 9215-9220 (2009-05-28)
Altering the specificity of an enzyme requires precise positioning of side-chain functional groups that interact with the modified groups of the new substrate. This requires not only sequence changes that introduce the new functional groups but also sequence changes that

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