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Key Documents

43963

Millipore

Moxalactam Supplement

suitable for microbiology

Synonym(s):

Listeria MOX Supplement

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About This Item

Empirical Formula (Hill Notation):
C20H20N6O9S
CAS Number:
Molecular Weight:
520.47
EC Number:
MDL number:
UNSPSC Code:
41171614
PubChem Substance ID:
NACRES:
NA.85

sterility

sterile

Quality Level

form

powder

shelf life

limited shelf life, expiry date on the label

application(s)

environmental
food and beverages

microbiology

storage temp.

2-8°C

suitability

Listeria spp.

SMILES string

CO[C@]2(NC(=O)C(C(O)=O)c1ccc(O)cc1)[C@H]3OCC(CSc4nnnn4C)=C(N3C2=O)C(O)=O

InChI

1S/C20H20N6O9S/c1-25-19(22-23-24-25)36-8-10-7-35-18-20(34-2,17(33)26(18)13(10)16(31)32)21-14(28)12(15(29)30)9-3-5-11(27)6-4-9/h3-6,12,18,27H,7-8H2,1-2H3,(H,21,28)(H,29,30)(H,31,32)/t12?,18-,20+/m1/s1

InChI key

JWCSIUVGFCSJCK-CAVRMKNVSA-N

General description

An antibiotic supplement recommended for selective isolation and cultivation of Listeria monocytogenes.

Application

for selective isolation and cultivation of Listeria monocytogenes

Components

(per vial, sufficient for 1000 ml medium)
Moxalactam 20.0 mg

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Xiaojun Wang et al.
Proteins, 47(1), 86-96 (2002-03-01)
The class A beta-lactamase TEM-1 is a key bacterial resistance enzyme against beta-lactam antibiotics, but little is known about the energetic bases for complementarity between TEM-1 and its inhibitors. Most inhibitors form a covalent adduct with the catalytic Ser70, making
Lionel Vercheval et al.
The Biochemical journal, 432(3), 495-504 (2010-11-27)
The activity of class D β-lactamases is dependent on Lys70 carboxylation in the active site. Structural, kinetic and affinity studies show that this post-translational modification can be affected by the presence of a poor substrate such as moxalactam but also
Sandrine Roisin et al.
Journal of clinical microbiology, 46(8), 2525-2528 (2008-06-14)
Detection of methicillin resistance in Staphylococcus aureus is a challenge, especially low-level resistance, which is often misdiagnosed. The aim of this study was to compare the diagnostic accuracies of the automated Vitek 2 system and disk diffusion tests, using cefoxitin
James Spencer et al.
Journal of the American Chemical Society, 127(41), 14439-14444 (2005-10-13)
Metallo-beta-lactamases are zinc-dependent enzymes responsible for resistance to beta-lactam antibiotics in a variety of host bacteria, usually Gram-negative species that act as opportunist pathogens. They hydrolyze all classes of beta-lactam antibiotics, including carbapenems, and escape the action of available beta-lactamase
J Scott Weese et al.
Anaerobe, 57, 35-38 (2019-03-19)
Clostridium (Clostridioides) difficile has been identified in humans and a wide range of animal species, but there has been little study of remote animal populations with limited human contact. The objective of this study was to determine the prevalence and

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