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43866

Supelco

Salidroside

analytical standard

Synonym(s):

2-(4-Hydroxyphenyl)ethyl β−D-glucopyranoside, p-Hydroxyphenethyl glucopyranoside, Rhodioloside, Rhodosin, Tyrosol a-(β-D-glucopyranoside)

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About This Item

Empirical Formula (Hill Notation):
C14H20O7
CAS Number:
Molecular Weight:
300.30
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥98.0% (HPLC)

optical activity

[α]/D -29±2°, c = 0.5 in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

OC[C@H]1O[C@@H](OCCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1

InChI key

ILRCGYURZSFMEG-RKQHYHRCSA-N

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General description

Salidroside is one of the major phenolic glycoside extracted from Rhodiola rosea L(, which can show a broad-spectrum of pharmacological properties like anti-aging, anti-oxidant, anti-cancer and anti-inflammation.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Salidroside, the 8-O-β-D-glucoside of tyrosol, is the main bioactive component of Rhodiola species and is found mainly in the plant roots. It is biosynthesised in the tyrosine metabolism, with glucosylation of tyrosol being the final step. It has been reported to be neuroprotective and one of the compounds responsible for the antidepressant and anxiolytic actions of Rhodiola rosea.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Ze-qiang Qu et al.
PloS one, 7(1), e29641-e29641 (2012-01-12)
Previously we have demonstrated that a Rhodiola crenulata extract (RCE), containing a potent antioxidant salidroside, promotes neurogenesis in the hippocampus of depressive rats. The current study was designed to further investigate the protective effect of the RCE on neurogenesis in
Wieland Peschel et al.
Phytochemistry, 86, 92-102 (2012-11-10)
The demand for plant material of Rhodiola rosea L. (Crassulaceae) for medicinal use has increased recently, amid concerns about its quality and sustainability. We have analysed the content of phenylpropanoids (total rosavins) and salidroside in liquid extracts from 3-year old
P T Linh et al.
Archives of pharmacal research, 23(4), 349-352 (2000-09-08)
A reversed-phase high performance liquid chromatographic method was developed to determine salidroside and tyrosol simultaneously in the Rhodiola rosea. The optimum condition was Nova-Pak C18 as stationary phase, 6.5% methanol in water as mobile phase and detection at UV 225
Xue Li et al.
Blood, 119(18), 4162-4173 (2012-03-20)
Salidroside is a phenylpropanoid glycoside isolated from the medicinal plant Rhodiola rosea, which has potent antioxidant properties. Here we show that salidroside prevented the loss of hematopoietic stem cells (HSCs) in mice under oxidative stress. Quiescent HSCs were recruited into
Lingling Zhang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(8), 2591-2597 (2012-06-06)
Oxidative stress plays an important role in the pathogenesis of Parkinson's disease (PD). Salidroside (SAL), a phenylpropanoid glycoside isolated from Rhodiola rosea L., can exert potent antioxidant properties. In this study, we investigated the protective effects, and the possible mechanism

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