IL038
Interleukin-1β Protein, Recombinant human
The recombinant human Interleukin-1beta protein (or IL-1beta protein) is a potent immuno-modulator which mediates a wide range of immune & inflammatory responses including the activation of B & T-cells.
Synonym(s):
IL-1beta
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About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.75
Recommended Products
biological source
human
Quality Level
Assay
>98% (SDS-PAGE and HPLC)
specific activity
>1 x 10e9 U/mg
manufacturer/tradename
Chemicon®
technique(s)
cell culture | mammalian: suitable
impurities
<0.1 ng/μg endotoxin (of human IL-1beta; 1EU/μg)
input
sample type hematopoietic stem cell(s)
NCBI accession no.
UniProt accession no.
shipped in
dry ice
General description
Interleukin-1beta (IL-1beta) is a potent immuno-modulator which mediates a wide range of immune and inflammatory responses including the activation of B and T-cells. Human IL-1beta is a 17.3 kDa protein containing 153 amino acid residues.
Application
For most in vitro applications, human IL-1beta is fully biological activity in the concentration range of 0.1 to 10.0 ng/mL. Responding cells are (partial list): Leukocytes.
Physical form
Sterile filtered and lyophilized from 10 mM Tris, pH 8.2 with no preservatives.
Storage and Stability
The lyophilized human IL-1beta, though stable at room temperature, is best stored desiccated at -20°C. After a quick spin, reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into other buffered solutions. Reconstituted human IL-1beta should be stored in undiluted aliquots at -20°C for up to six months.
Analysis Note
Specific Activity: Chemicon′s human IL-1beta is fully biologically active when compared to standards.The ED(50) as determined by the dose-dependent stimulation of the proliferation of murine D10S cells is <0.001 ng/mL
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
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