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Sigma-Aldrich

Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6, Alexa Fluor™ 488

clone C464.6, Upstate®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

ALEXA FLUOR™ 488

antibody form

purified antibody

antibody product type

primary antibodies

clone

C464.6, monoclonal

species reactivity

pig, rat, Xenopus, human, rabbit, mouse, monkey, canine

packaging

antibody small pack of 25 μg

manufacturer/tradename

Upstate®

technique(s)

flow cytometry: suitable
immunocytochemistry: suitable
western blot: suitable

isotype

IgG1κ

NCBI accession no.

NM_152296.3

UniProt accession no.

Q9N0Z6

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ATP1A3(478)

Related Categories

Specificity

Specific for the α-1 subunit isoform.

Immunogen

Purified Na+/K+ ATPase isolated from membrane fractions of rabbit kidney outer medulla.

Application

Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
This Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6, Alexa Fluor 488 is validated for use in FC, IC, WB for the detection of Na+/K+ ATPase α-1.

Quality

Routinely evaluated by immunoblot.

Target description

112kDa

Physical form

Protein G Purified

Storage and Stability

2 years at 4°C from date of shipment

Legal Information

ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Alexa Fluor™ is a registered trademark of Molecular Probes, Inc.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Antibody development and use in chromogenic and fluorescent immunostaining.
Eamon Dubaissi,Niki Panagiotaki,Nancy Papalopulu,Peter D Vize
Methods in Molecular Biology null
Zijian Xie et al.
Molecular interventions, 3(3), 157-168 (2004-03-03)
The Na+-K+--ATPase, or Na+ pump, is a member of the P-type ATPase superfamily. In addition to pumping ions, Na+-K+--ATPase is engaged in assembly of multiple protein complexes that transmit signals to different intracellular compartments. The signaling function of the enzyme
L Garcia-Rodríguez et al.
Gene therapy, 18(1), 73-81 (2010-08-20)
The thymidine kinase/ganciclovir (TK/GCV) cancer gene therapy approach is based on inducing GCV metabolite cytotoxicity in tumor cells expressing the herpes simplex virus TK gene and exposed to GCV. A bystander effect, mediated by gap junctions, accounts for the transfer
Na/K-ATPase, endogenous digitalis like compounds and cancer development -- a hypothesis.
Weidemann, Heidrun
Frontiers in Bioscience, 10, 2165-2176 (2005)
Neuronal function and alpha3 isoform of the Na/K-ATPase.
Dobretsov, Maxim and Stimers, Joseph R
Frontiers in Bioscience, 10, 2373-2396 (2005)
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